In a nutshell This study reported the long-term safety and effectiveness of nivolumab (Opdivo; N) + AVD (doxorubicin, vinblastine, and dacarbazine) chemotherapy combinations in patients with early-stage unfavorable classical Hodgkin lymphoma (cHL). The data showed that the N+AVD combination is safe and highly effective over the long term for these...
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Evaluating the effectiveness and safety of brentuximab vedotin plus nivolumab consolidation therapy after autologous hematopoietic stem-cell transplantation in patients with high-risk classic Hodgkin lymphoma.
In a nutshell This study evaluated the effectiveness and safety of brentuximab vedotin (BV; Adcetris) plus nivolumab (Opdivo) consolidation therapy after autologous hematopoietic stem-cell transplantation (HSCT) in patients with high-risk relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The data showed that the BV plus nivolumab combination...
Read MoreEvaluating the effectiveness and safety of pembrolizumab for the treatment of patients with relapsed or refractory classical Hodgkin lymphoma before stem cell transplantation.
In a nutshell This study evaluated the effectiveness and safety of pembrolizumab (Keytruda) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL) before stem cell transplantation. The data showed that pembrolizumab was effective and safe with manageable side effects in these patients. Some background...
Read MoreEvaluating the risk of cardiovascular disease mortality among long-term survivors of classical Hodgkin lymphoma.
In a nutshell This study evaluated the risk of cardiovascular disease mortality among long-term survivors of classical Hodgkin lymphoma (cHL). The data showed that patients with early-stage HL are at a higher risk of mortality from cardiovascular disease than from cancer. Some background cHL is a cancer that starts in white blood cells called...
Read MoreEvaluating the effectiveness and safety of penpulimab in patients with relapsed or refractory classical Hodgkin lymphoma.
In a nutshell This study evaluated the effectiveness and safety of penpulimab (AK105) for the treatment of patients with relapsed or refractory (r/r) classical Hodgkin lymphoma (cHL). The data showed that penpulimab was effective and safe with manageable side effects in these patients. Some background Classical Hodgkin lymphoma (cHL) is a cancer of...
Read MoreHow effective is whole-body MRI as an imaging technique for measuring treatment responses in patients with blood cancers?
In a nutshell This study assessed the accuracy of whole-body (WB) magnetic resonance imaging (MRI) in evaluating the treatment response of blood cancers. The data indicated that WB-MRI had a high diagnostic performance for assessing the treatment response of blood cancers and its addition was strongly linked to better diagnostic...
Read MoreEvaluating the impact of immunetherapy on COVID-19 outcomes in patients with cancer.
In a nutshell This study evaluated the impact of immune checkpoint inhibitors (ICIs) on COVID-19 outcomes in patients with cancer. The data showed that the use of ICI treatment before COVID-19 infection does not affect the disease severity or survival outcomes. This study supports the continued use of ICIs in cancer patients during the pandemic. Some...
Read MoreEvaluating response to SARS-CoV-2 vaccination in patients with blood cancers
In a nutshell The study aimed to investigate the rate of response (seroconversion) to SARS-Cov-2 vaccination in patients with blood cancers. This study concluded that seroconversion rates in these patients were significantly lower than that of healthy controls. Some background The severe acute respiratory syndrome...
Read MoreEvaluating the mental function in long-term survivors of Hodgkin lymphoma.
In a nutshell This study evaluated the cognitive (mental abilities) function of long-term survivors of Hodgkin lymphoma (HL). The data showed that long-term survivors of HL with inactive employment status and older age showed impaired cognitive function. Some background HL is a cancer that involves the lymphatic system and affects how...
Read MoreEvaluating brentuximab-vedotin with bendamustine combination treatment before transplantation in patients with relapsed/refractory Hodgkin lymphoma
In a nutshell This study aimed to investigate the safety and effectiveness of brentuximab-vedotin (Bv; Adcetris) combined with bendamustine (Treanda: B) as salvage treatment in patients with relapsed/refractory (r/r) classical Hodgkin lymphoma (cHL). This study concluded that this treatment is safe and effective in these patients....
Read MoreEvaluating COVID-19 vaccination in immunocompromised patients with blood cancers
In a nutshell The study aimed to investigate if immunocompromised patients with blood cancers benefit from COVID-19 vaccination. This study concluded that these patients should not be excluded from COVID-19 vaccination. Some background Patients with blood cancers are at high risk for severe forms of COVID-19 disease due to lower...
Read MoreVacations for Adult Cancer Patients: Update
Two of our most popular previous blog posts described free vacation opportunities for adults with cancer. Given the uncertainty of the past two years, we thought it was time for an update. Here is a short list of organizations that have made it their mission to provide needed respite to those affected by cancer. Each has been verified to have...
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