In a nutshell The aim of this phase 1 trial is to study the effectiveness of treatment with AZD1775 combined with the chemotherapy irinotecan (Camptosar). The main outcome to be measured is the tumor response to the treatment and toxicity. The details Chemotherapy is a standard treatment to colorectal cancer. It reduces symptoms and prolongs...
Read More
In a nutshell The aim of this phase 2 trial is to compare the effectiveness of the combined treatment with chemotherapy, avelumab (Bavencio) and the vaccine Ad-CEA in patients with metastatic (spread to other parts of the body) colorectal cancer. The main outcome to be measured is tumor response to the treatment. This trial will recruit in Maryland,...
Read More
In April, the American Association for Cancer Research (AACR) held a free education event on cancer called Progress and Promise Against Cancer in Washington, D.C. Surrounded by experts in cancer research, Kim Hall Jackson shared her patient story. One evening in 2008, Jackson, an event planner, was running the mayor’s inaugural event in...
Read More
In July 2015, we published a post called Patients Included In Research: Studying Cancer by Mutation Not Organ. In that post, we shared the goal that cancers would be treated not by the site of origin, but rather by their genetic features. Achieving this goal is closer than you think! This week the FDA announced accelerated approval** of a...
Read MoreIn a nutshell This study investigated the effects of surgery and post-surgery chemotherapy in elderly stage 3 colon cancer patients. Researchers reported that post-surgery chemotherapy improves long-term survival of these patients. Some background Surgery and post-surgery chemotherapy are the standard treatment for stage 3 colon cancer. Several...
Read More
In a nutshell This study investigated the impact of laparoscopic (LPS) compared with open surgery on colorectal liver metastasis (when cancer spreads to the liver). Researchers suggested that LPS is a safe option to treat liver metastasis in colorectal cancer patients. Some background The liver is the most common site of colorectal cancer...
Read More
In a nutshell This study investigated the effectiveness of the chemotherapy FOLFOX plus cetuximab (Erbitux), after cancer progression with FOLFIRI plus cetuximab. Researchers suggested that FOLFOX plus cetuximab is an important treatment option in non-KRAS mutated metastatic (spread to other parts of the body) colorectal cancer. Some background...
Read More
In a nutshell This study investigated the predictive factors of malignant large bowel obstruction (MLBO) in incurable stage 4 colorectal cancer. Researchers suggested that MLBO is associated with tumor ulceration (when a tumor breaks through the skin’s surface), location and width. Some background An MLBO is a blockage of the intestine which...
Read More
We are adding to the list of respite opportunities that are available for adults with cancer. In addition to a couple of programs like the ones featured in Free Vacations for Adults affected by Cancer, there are a few foundations for adults with cancer that are much like the well-known Make-A-Wish Foundation (for children) which provide support for...
Read More
In a nutshell This study compared the functional outcomes of the urinary and sexual organs after a robotic (RRS) or laparoscopic rectal cancer surgery (LRS). Researchers suggested that the robotic rectal surgery offers better post-surgery recovery of these organs. Some background Rectal cancer surgery is associated with a high risk of urinary and...
Read More
In a nutshell This study investigated the effect of coffee intake in stage 3 colon cancer. Researchers suggested that an increased coffee intake is associated with a lower risk of cancer recurrence (when the cancer comes back) and improved survival. Some background High levels of insulin in the blood, inactive lifestyle, obesity and diet with high...
Read MoreIn a nutshell This study investigated the prognostic role of the lymph node ratio (LNR; number of lymph node metastasis per lymph nodes removed) in stage 3 colorectal cancer following post-surgery chemotherapy. Researchers suggested that LNR is strongly associated with recurrence risk (when the cancer comes back) in these patients. Some...
Read More
