In a nutshell This study investigated adjuvant (after surgery) chemotherapy in HER2-positive breast cancer (BC). They found that survival rates were similar across chemotherapy regimens. Some background Breast cancer (BC) is a very common and treatable form of cancer. Survival rates in BC have been improved by targeted therapies....
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In a nutshell This study evaluated the impact of radiotherapy on the survival of patients with breast cancer who have undergone surgery. This study found that patients who had radiotherapy after surgery had higher survival than patients who had surgery only. Some background Triple-negative breast cancer (TNBC) is cancer that does not have...
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In a nutshell This phase 3 trial will investigate the effectiveness of pembrolizumab (Keytruda) in combination with pre-surgery chemotherapy and after-surgery hormonal therapy in patients with high-risk early-stage breast cancer (BC). The main outcomes to be measured will be the response to treatment and survival. The details...
Read MoreIn a nutshell This study investigated if an exercise regimen improved shoulder function in breast cancer survivors who received surgery to remove underarm lymph nodes. They found that both inflatable ball exercise and control standard exercise were beneficial for these patients. Some background Breast cancer (BC) is the most common cancer...
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In a nutshell This study investigated the effectiveness of exercise therapy to treat joint pain in patients with breast cancer (BC) treated with aromatase inhibitors (AIs). They found that the overall quality of life was improved after 12 months of exercise therapy in these patients. Some background Breast cancer is the most common cancer...
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In a nutshell This study investigated patient-reported outcomes related to radiotherapy (RT) for breast cancer. They found that patients were dissatisfied with outcomes after RT but this was not a long-term effect. Some background Breast cancer is the most common form of cancer in women. A number of strategies are used to treat BC. A lot of BC cases...
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In a nutshell This phase 3 trial will investigate the effectiveness and safety of ribociclib (Kisquali) in breast cancer (BC). The main outcome will be the rate of survival without disease. The details Breast cancer (BC) is a common form of cancer. Cancers, including BC, can be categorized depending on certain proteins. Some BCs...
Read MoreIn a nutshell This phase 3 trial will investigate the effectiveness of 2 experimental drugs, DS-8201a vs T-DM1, for the treatment of breast cancer (BC). The main outcome will be survival without cancer worsening. The details Breast cancer (BC) is a common and treatable form of cancer. Cancers, including BC, can be categorized depending on certain...
Read MoreIn a nutshell The trial aims to investigate a new way of delivering radiation therapy in women with early-stage breast cancer. This will involve low doses of radiation therapy being aimed at the part of the breast where the tumor is or was. The main outcomes that will be measured are side effects and recurrence rate. This trial is recruiting in Missouri,...
Read MoreIn a nutshell This phase 3 trial will investigate the effectiveness of a new drug, DS-8201a, in the treatment of unresectable/metastatic breast cancer (UMBC). The main outcome will be survival without cancer worsening. The details Breast cancer (BC) originates from tissue in the breast. BC is treated with surgery to remove the cancer or...
Read MoreIn a nutshell This trial aims to find out if targeted radiotherapy on the breast in women with low-risk breast cancer after breast-conserving surgery will prevent the cancer from coming back. The main outcome that will be measured is how long it takes before the breast cancer comes back. The study is being conducted in Canada and the United States. The...
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In a nutshell This study wanted to analyze the outcomes of patients with breast cancer that has come back into the brain and who needed salvage radiotherapy to the brain. The study found that performing radiotherapy on the brain was effective in controlling the cancer in these patients. Some background Breast cancer can often spread...
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