In a nutshell
This study investigated if garlic supplementation improves rheumatoid arthritis (RA) symptoms. They found that garlic supplementation improved RA inflammation and symptoms.
Some background
Rheumatoid arthritis (RA) is a chronic immune condition. It is caused by excess inflammation. It leads to painful swelling in the joints. It eventually leads to disability. RA is treated with drugs that reduce inflammation. Some studies suggest alternative medicines could reduce disease activity (DA) in RA.
Garlic is a food rich in compounds that reduced inflammation. Studies have shown that these compounds can improve the immune system function. Some studies also suggest that these compounds can reduce inflammation in diseases. Garlic has also been shown to relieve pain and fatigue in certain conditions. It is unclear if garlic supplementation improves DA in patients with RA.
Methods & findings
This study included 70 women with RA. Patients were randomly assigned to 500 mg garlic powder tablets twice a day or placebo. Treatment lasted 8 weeks. Patients also took their usual RA medication. DA was measured using the DAS28 score. Blood samples were taken to measure chemicals and proteins involved in inflammation. These included c-reactive protein (CRP) and tumor necrosis factor (TNF). Pain was also measured.
At the end of 8 weeks, CRP and TNF levels were significantly reduced in the garlic group. After 8 weeks, DAS28 scores were also significantly lower in garlic-treated patients. Pain intensity and fatigue scores were also significantly improved in the garlic group.
The bottom line
The authors concluded that garlic supplementation improved RA symptoms and inflammation.
The fine print
The study duration was relatively short. We do not know if garlic supplementation will continue to improve DA after 8 weeks. Long-term studies are needed.
What’s next?
If you have any concerns regarding RA management please discuss it with your physician.
Published By :
Phytotherapy research : PTR
Date :
Jun 01, 2020
