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Posted by on May 29, 2015 in Lung cancer | 0 comments

In a nutshell

The authors aimed to assess whether collaboration of different healthcare professionals can help treat non-small cell lung cancer (NSCLC) patients better and improve overall survival.

Some background

Treatment of NSCLC is decided based on the stage of the cancer. In the early stage (I/II), surgery and chemotherapy are the standard treatments.  In the advanced stage (III/IV), radiation therapy and other treatments are also needed to ease the symptoms and improve the quality of life. Therefore, collaboration and coordination between different healthcare professionals is required at different stages of the cancer. This group of health professionals is called a multidisciplinary team (MDT) consisting of cancer specialists, radiotherapists, nurses, social workers and many other members. Previous studies have shown that MDT care can improve the overall survival in pancreatic and breast cancer patients. However, the effect of MDT care on different stages of NSCLC has not yet been evaluated.

Methods & findings

To evaluate the effect of MDT care, the authors analyzed data from 32,569 patients diagnosed with NSCLC between 2005-2010. All patients had received treatment within the first year of diagnosis. Based on the stage of cancer, patients were divided into two groups : stage I / II and stage III / IV. 
 
The survival rates of MDT participants and non-participants were compared over 2 year period. For stage I, the survival rate was 81% for MDT participants compared to 78% for non-participants. For stage II, the survival rate was 64%  for MDT participants compared to 59% for non-participants. For stage III, the survival rate was 37% for MDT participants compared to 31% for non-particpinats. For stage IV, the survival rate was 22% for MDT participants compared to 20% for non-participants.
 
Overall, among the patients at stage III and IV, MDT participants had 13% reduced risk of death compared to MDT non-participants. For patients at stage I and II, participation in MDT care did not improve the survival rates significantly.

The bottom line

The authors concluded that participation in the MDT care program helped improve overall survival of patients at stage III and IV NSCLC.

The fine print

Several factors were not taken into account while adjusting the outcome of MDT care. These were smoking, occupation, specific lifestyles, and tumor locations among others. Also, change of physician/hospital during the course of treatment could have altered the quality of MDT care program.

Published By :

PLOS ONE

Date :

May 12, 2015

Original Title :

Effects of Multidisciplinary Team Care on the Survival of Patients with Different Stages of Non-Small Cell Lung Cancer: A National Cohort Study.

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