In a nutshell
This study investigated the success rates of in vitro fertilization (IVF) following either frozen or fresh embryo transfer. They found that frozen-thawed embryo transfer resulted in higher pregnancy and birth rates.
Some background
To treat infertility embryos are artificially fertilized using techniques such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Fertilized embryos can be implanted into the uterus immediately, or frozen for implantation into the uterus at a later stage.
It is unclear if fresh embryo transfer (ET) or frozen-thawed embryo transfer (FET) is more successful in the treatment of infertility.
Methods & findings
This study investigated the pregnancy and birth rates of ET versus FET in women seeking treatment for infertility.
This study analyzed data from 7 clinical reports. In these reports, patients underwent wither ET or FET. The authors compared implanation, pregnancy and live birth rates in these patients. They also investigated the rates of miscarriage and ovarian hyperstimulation syndrome (OHSS, a complication where the overies become swollen and painful).
Pregnancy rates and live birth rates were significantly higher in women that underwent FET. FET was also associated with reduced miscarriage and OHSS rates.
The bottom line
The authors concluded that frozen-thawed embryo transfer resulted in higher pregnancy and birth rates.
The fine print
Embryo quality can have a significant effect on the success of IVF, this data was not available to the authors. The authors recommend that all patients should be made aware of the advantages, disadvantages, and risks associated with embryo freezing.
What’s next?
If you have any concerns regarding fertility treatment, please discuss this with your physician.
Published By :
Archives of Gynecology and Obstetrics
Date :
Jun 07, 2018
