In a nutshell
This study reviewed the management of anabolic steroid (AS) induced infertility.
Some background
Testosterone (TTS) is a male sex hormone. It has a number of functions including sperm production. Thus, it is an important fertility hormone. TTS is also described as an androgenic-anabolic steroid (AAS). Taking synthetic TTS is associated with fertility problems. The reasons for taking TTS are varied. Some men may have low TTS production. Others may take TTS recreationally. It can improve athletic performance.
Managing infertility in these patients can be difficult. Some patients require TTS treatment. Reviewing treatment strategies can be helpful to optimize patient care.
Methods & findings
There are many options for recovery of fertility. The first option is to cease TTS or other AAS use. This can lead to a recovery in sperm production. This can take a considerable length of time. Patients should begin a regimen of drugs to stimulate fertility. This includes human chorionic gonadotrophin (HCG) and clomiphene citrate (CC). HCG stimulates the release of TTS in the testicles. CC stimulates the release of natural HCG and thus TTS. Using these medications allows a ‘normal’ level of TTS production.
Regular semen analysis should be performed. Semen analysis determines if there are fertility issues. Further investigation can be performed if semen analysis results are negative. Genetic tests can be performed for men with no sperm production. Cryopreservation (freezing) can be offered to men with low sperm count.
To maintain fertility while receiving TTS, several options can be used. The treatment regimen should depend on the desired timing of pregnancy. If pregnancy is desired within 6 months, treatment with HCG/CC should be used. A combination of TTS/AAS and HCG/CC should be used for pregnancy 6-12 months. To achieve pregnancy after 12 months TTS/AAS and HCG should be used.
The bottom line
This study reviewed the management of anabolic steroids-induced infertility.
The fine print
These are general recommendations. Each patient will require individual-tailored treatment.
What’s next?
If you have any concerns regarding infertility, please consult with your physician.
Published By :
The world journal of men’s health
Date :
Mar 26, 2019
