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Posted by on May 21, 2016 in Diabetes mellitus | 8 comments

In a nutshell

The purpose of this study was to examine the association between type 1 diabetes mellitus (T1DM) and the risk of herpes zoster (HZ). The study concluded that patients with T1DM are at a higher risk of HZ than people without T1DM.

Some background

Patients with diabetes have an impaired regulation of their immune system. In general, patients with diabetes are more prone to infections than those without diabetes. Herpes zoster is the virus that can causes chickenpox and shingles. The symptoms of chickenpox are a mild fever and a rash of itchy inflamed pimples that turn to blisters and then scabs. This mainly affects children. The virus that causes chickenpox and shingles is not the same virus responsible for cold sores or genital herpes, a sexually transmitted infection. It is unclear whether there is an association between the herpes zoster virus and diabetes.

Methods & findings

This study included 4,736 patients with T1DM receiving insulin therapy. The study also included 18,944 participants without diabetes. They measured the risk of HZ in the T1DM group compared to the non-T1DM group.

Patients with T1DM were more than twice as likely to have the herpes zoster virus than those without T1DM. Those with serious T1DM (those with more complications due to the disease) were 5 times more likely to have the herpes zoster virus.

The bottom line

The current study concluded that patients with T1DM are at a higher risk of HZ than people without T1DM.

The fine print

This study was carried out in an Asian population and therefore the risk of HZ in other populations may differ.

Published By :

PLOS ONE

Date :

May 12, 2016

Original Title :

Association of Herpes Zoster and Type 1 Diabetes Mellitus.

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