In a nutshell
This study investigated if there are risks associated with antidepressant (ATD) use after a heart attack (myocardial infarction, MI).
They found that ATD use was associated with higher mortality (death) risk after MI.
Some background
Myocardial infarction (MI) is the medical term for a heart attack. Antidepressants (ATDs) are used to treat conditions such as depression and anxiety. ATDs are commonly prescribed by doctors nowadays. As a result, many patients that have an MI may be taking ATDs. It is unclear if ATD use poses a risk to patients after MI.
Methods & findings
This study included 9253 patients. All patients were recovering from an MI. Patient information was assessed on enrollment to the study. One year later, follow-up assessment was performed. This involved a phone interview. The authors investigated the mortality risk of ATD use after MI.
6.3% of patients were taking ATDs at the beginning of the study. Patients taking ATDs were more likely to be older females with a history of heart disease. They were also more likely to have other conditions such as diabetes and obesity. After 1 year, 22% in both groups reported feeling well. The mortality risk 1 year after MI was 66% higher in patients that took ATDs.
The bottom line
The authors concluded that ATD use was associated with higher mortality risk after MI.
The fine print
This study did not include some very important information. The reason for ATD use and type of ATD was not available. More investigation is needed to confirm these findings.
What’s next?
If you have any concerns regarding heart disease treatment or depression, please consult with your physician.
Published By :
European Heart Journal
Date :
Feb 01, 2019
