In a nutshell
This study aimed to investigate the use of cholecalciferol (vitamin D3) for the prevention of recurrent urinary tract infections (UTIs) for men with benign prostate hyperplasia (BPH). This study found that vitamin D3 supplementation may be protective against recurrent UTIs among patients with BPH.
Some background
People diagnosed with BPH (non-cancerous overgrowth of the prostate) can experience urinary tract infections (UTIs). Tamsulosin (Flomax) can be used to treat BPH symptoms by relaxing bladder muscles. This makes it easier to urinate.
A low cholecalciferol (vitamin D3) level has been associated with an increased frequency of infections. However, the relation between vitamin D3 and UTIs in patients with BPH has not been evaluated.
Methods & findings
This study included 389 patients with moderate to severe BPH. In group A, 193 patients were treated with tamsulosin alone. Group B included 196 patients who received tamsulosin and vitamin D3. They were followed up for 2 years.
Patients in group A experienced recurrent UTIs more frequently (13.5%) than those in group B (4.6%). Patients in group B were 90% more likely to have lower PSA levels (a protein found in the blood that can be used to monitor treatment of BPH) at the end of treatment.
The bottom line
This study found that vitamin D3 may be protective against recurrent UTIs among patients with BPH.
The fine print
Patients in this study did not have confirmed vitamin D3 deficiency. This missing information might have affected the results of the study.
What’s next?
If you have concerns about vitamin D levels and supplementation, please consult with your doctor.
Published By :
World Journal of Urology
Date :
Oct 25, 2018
