In a nutshell This article reviewed the use of anti-inflammatory medications as treatment for colorectal cancer. Some background Colorectal cancer (CRC) is the second most common cause of cancer-related death in the United States. Despite new therapeutic techniques, survival rates among CRC patients remain low. Therefore, research into new...
Read MoreIn a nutshell In this study, researchers examined how adjuvant chemotherapy benefits colon cancer patients over the age of 75. Some background Adjuvant chemotherapy (the addition of chemotherapy to another treatment, such as surgery) has been shown to benefit survival in multiple trials and is considered common practice for patients with advanced...
Read MoreIn a nutshell This meta-analysis (an analysis of data combined from several similar studies) investigated the efficiency of FDG-PET and PET/CT in detecting the recurrence of colorectal cancer in patients with elevated carcinoembryonic antigen (CEA). Some background Colorectal cancer often recurs (comes back) after initial treatment. CEA is a...
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In a nutshell This study assessed the efficiency of bevacizumab (avastin) treatment in patients with metastatic colorectal cancer. The association between the effectiveness of treatment and the location of the primary tumor was examined. Some background Colorectal cancer can originate from different sections of the large intestines. The origin of...
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In a nutshell This study examined whether type 2 diabetes mellitus had any influence on survival in patients with colorectal cancer. Some background Type 2 diabetes mellitus (T2DM) is known to be associated with many types of cancer, including colorectal cancer (CRC). T2DM is also associated with an increased risk of other health problems...
Read MoreIn a nutshell This study compared the ability of two drugs, ganitumab and conatumumab, to treat patients with metastatic colorectal cancer when added to chemotherapy. Some background Cancer cells express various structures on their surface (called receptors) that may stimulate growth and help avoid destruction by the immune system. Drugs that...
Read MoreIn a nutshell This study explored whether cetuximab (erbitux) can benefit patients with unresectable colorectal liver metastases. The ability to perform surgery to remove part or all of the tumor growth in the liver (the resection rate) was compared between patients receiving cetuximab in combination with chemotherapy, to those receiving chemotherapy...
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In a nutshell This study examined how often surveillance colonoscopies should be performed following curative surgery for colorectal cancer (CRC). Some background In the years following curative surgery for colorectal cancer (surgery to remove all of the tumor and nearby affected tissues) surveillance tests such as colonoscopies and imaging scans...
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In a nutshell The aim of this study was to evaluate the frequency of serrated polyps (tissue growths with a saw tooth appearance under the microscope) and their association with colorectal cancer (CRC). Some background Colorectal polyps are tissue growths on the inner lining of the large intestine. They are usually benign (non-cancerous)...
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In a nutshell This study examined whether dietary supplements, such as a multivitamins, are associated with the recurrence (return) of colorectal adenomas (polyps). Some background Colorectal adenomas or polyps are non-cancerous growths on the lining of the large intestine. After being removed, colorectal adenomas can reoccur. Although...
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In a nutshell This study aimed to identify risk factors for recurrence (return of the cancer) in patients with colorectal cancer following surgical removal. Some background Colorectal cancer (CRC) is one of the most commonly diagnosed cancers. Treatment for CRC has generally involved surgery to remove the cancer along with the entire area...
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In a nutshell The present review evaluated the benefits of histamine type 2 receptor antagonists or H2RA (a type of drugs used for the treatment of stomach ulcers) before or after surgery in patients with colorectal cancer (CRC). Some background CRC is cancer in the large intestine. In the early stages (when it is confined to the bowel), CRC is...
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