In a nutshell This study examined how often and why patients are readmitted to hospital within 90 days of colorectal cancer surgery. Some background Treatment for colorectal cancer often involves surgery, which can be followed by chemotherapy. After a short recovery period in hospital most patients will continue their recovery at home....
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In a nutshell This study evaluated the association between lifestyle factors and mortality in colorectal cancer. Some background To date, few studies have examined the relationship of lifestyle factors with mortality among patients with colorectal cancer. The American Cancer Society Guidelines on Nutrition and Physical Activity for Cancer...
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In a nutshell This review analyzed recent research investigating the effects of aspirin on colorectal cancer outcomes. Some background Aspirin is a common anti-inflammatory drug often used to relieve pain and reduce fever. The anti-inflammatory properties of aspirin are associated with its ability to inhibit the actions of the enzyme...
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In a nutshell This study investigated the association between survival and beta-blocker use in colorectal cancer. Some background Colorectal cancer is one of the most common malignant diseases worldwide. Despite recent advances in treatments such surgery, chemotherapy and radiotherapy, survival rates among advanced colorectal cancer patients...
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In a nutshell This study analyzed data from the national cancer surveillance program in order to compare between the characteristics and outcomes of patients with colon and rectal cancer. Some background Colon and Rectal cancer are the third most common causes of cancer in the United States. The clinical presentation, diagnosis and treatment of...
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In a nutshell The current study examined whether the proteins versican and lumican were predictive of prognosis among colon cancer patients. Some background Colon cancer treatments vary depending on the type and stage of the disease. Patients with advanced cancer, which has invaded the surrounding lymph nodes, usually receive chemotherapy along...
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In a nutshell This study estimated survival gain with the addition of aflibercept (Zaltrap) to standard chemotherapy among patients with metastatic colorectal cancer. Some background A combination chemotherapy regimen referred to as FOLFIRI (folinic acid, 5-fluorouracil and irinotecan) is considered the standard of care in the treatment of...
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In a nutshell This study evaluated the use of capecitabine in combination with bevacizumab (Avastin) in the treatment of unresectable metastatic colorectal cancer. Some background Current treatment of unresectable metastatic colorectal cancer (wide spread cancer that cannot be removed by surgery do to size or location) includes chemotherapy, such...
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In a nutshell This review explored the relationship between dietary supplements and colorectal cancer outcomes. Some background The prevalence of colorectal cancer has steadily increased over the past 50 years. Dietary changes and decreased physical activity have led to an obesity epidemic in the western world, a known risk factor for many...
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In a nutshell This study examined the effectiveness and safety of a new chemotherapy combination including oxaliplatin, irinotecan, and S-1 for the treatment of metastatic colorectal cancer. Some background For several years, standard chemotherapy for metastatic colorectal cancer (a cancer which has spread to other organs) included a combination...
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In a nutshell This trial investigated the association between physical activity and the risk of recurrence (return of the cancer) and survival in patients with colon cancer (cancer of the large intestine). Some background The treatments of colon cancer have improved significantly over the years. However, many patients still have high risks for...
Read MoreIn a nutshell This study investigated the combination of hepatic artery infusion (HAI) and systemic chemotherapy for the treatment of unresectable colorectal cancer liver metastasis (CRLM). Some background The liver is the most common site of metastasis (cancer spread) in colorectal cancer patients. Surgical treatments that remove all liver tumors...
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