Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the rectum Posts on Medivizor
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Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the rectum Posts on Medivizor

The effectiveness and safety of regorafenib in older patients with advanced pretreated colorectal cancer

The effectiveness and safety of regorafenib in older patients with advanced pretreated colorectal cancer

Posted by on May 24, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of regorafenib (Stivarga) treatment in older patients with colorectal cancer (CRC). Researchers suggested that this treatment has similar effects in younger and older patients. Some background CRC is the third most common cancer worldwide. More than half are diagnosed in patients older...

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How common are late side effects after radiation treatment for rectal cancer?

Posted by on May 9, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the frequency of late gastrointestinal (GI) side effects after radiation therapy (RT) for rectal cancer. Researchers suggested that after the improvement of RT methods these side effects are less frequent and less severe. Some background Colorectal cancer is one of the most frequently diagnosed cancers in the...

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Pelvic radiotherapy followed by systemic therapy and surgery improves survival in patients with advanced rectal cancer

Posted by on Feb 22, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of pelvic radiotherapy (PRT) followed by chemotherapy and surgery in advanced rectal cancer. Researchers suggested that this combined treatment is associated with improved survival rates. Some background Rectal cancer affects 44,180 people each year in the US. Up to 80% of these people present...

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TAS-102 plus bevacizumab treatment in patients with metastatic treatment-resistant colorectal cancer

Posted by on Feb 21, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the safety and effectiveness of TAS-102 (trifluridine-tipiracil) with and without bevacizumab (Avastin) therapy in metastatic colorectal cancer (mCRC). Researchers suggested that this combined therapy might be a good treatment option for patients with advanced CRC. Some background Colorectal cancer is the third...

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Does chemotherapy after surgery improve survival in high-risk stage 2 colorectal cancer?

Posted by on Feb 19, 2020 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of chemotherapy after surgery in stage 2 colorectal cancer (CRC). Researchers suggested that this treatment may result in survival improvement but should be individualized. Some background CRC affects 145,600 adults in the US every year. Treatment for this disease is guided by stage at...

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A longer interval between chemoradiotherapy and surgery improves rectal cancer outcomes

Posted by on Dec 23, 2019 in Colorectal cancer | 0 comments

In a nutshell This study compared the effects of different time intervals between chemotherapy and radiation therapy (CRT) and rectal cancer surgery. Researchers suggested that increasing this interval from 8 weeks to 12 weeks improved treatment response. Some background Over 70% of patients with rectal cancer have locally advanced disease at...

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Chemotherapy improves survival of patients with mucinous colorectal adenocarcinoma

Posted by on Dec 7, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effect of chemotherapy on the survival of patients with stage 2 and 3 mucinous colorectal cancer (mucCRC). Researchers suggested that chemotherapy improved the survival of these patients. Some background Colorectal cancer is the third most common cancer in the US in 2019. Up to 20% of colon cancer is mucCRC....

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Looking for participants with advanced colorectal cancer to test a combination therapy

Posted by on Sep 25, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1/2 trial is examining the effectiveness of standard therapy alone or combined with new drugs as first line treatment for advanced colorectal cancer. The main outcome to be measured will be safety and tumor response to the treatment.  The details Colorectal cancer is one of the most common cancers worldwide. A significant...

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Looking for participants to test a vaccine for the treatment of advanced colorectal cancer

Posted by on Sep 10, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1b trial is examining the effectiveness and safety of a vaccine treatment, ATP128, in the treatment of advanced colorectal cancer. The main outcome to be measured is the tumor response to the treatment and treatment toxicity. This trial is being conducted in Arizona and California, US. The details Colorectal cancer is the...

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Looking for participants with metastatic melanoma to test a new immunotherapy

Posted by on Aug 14, 2019 in Melanoma | 0 comments

In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...

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The role of chemotherapy after surgery in patients with rectal cancer with a complete response after pre-surgery treatment

Posted by on Jul 30, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the impact of chemotherapy after surgery (CAS) in patients with rectal cancer who had a complete response to chemotherapy before surgery. Researchers suggested that the routine use of CAS should not be recommended in these patients. Some background Colorectal cancer is one of the most common cancer...

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Looking for participants with advanced cancer to test a new therapy

Posted by on Jul 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This trial is examining the effectiveness and toxicity of COTI-2 treatment in patients with advanced cancer. The main outcomes to be measured will be cancer response to the treatment and number of side effects. This study is being conducted in Texas, US. The details Cancer resistance to therapy affects successful cancer treatment. The...

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