Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the rectum Posts on Medivizor
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Type(s) of colorectal cancer (CRC)-Adenocarcinoma of the rectum Posts on Medivizor

Looking for participants to test a vaccine for the treatment of advanced colorectal cancer

Posted by on Sep 10, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 1b trial is examining the effectiveness and safety of a vaccine treatment, ATP128, in the treatment of advanced colorectal cancer. The main outcome to be measured is the tumor response to the treatment and treatment toxicity. This trial is being conducted in Arizona and California, US. The details Colorectal cancer is the...

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Looking for participants with metastatic melanoma to test a new immunotherapy

Posted by on Aug 14, 2019 in Melanoma | 0 comments

In a nutshell This phase 1 trial is examining the effectiveness of personalized tumor antigens (PTA) in the treatment of different advanced tumors. The main outcomes to be measured will be side effects and disease control. This study is being conducted in Arizona, California, Louisiana and New Jersey, US. The details While the tumor cells are growing,...

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The role of chemotherapy after surgery in patients with rectal cancer with a complete response after pre-surgery treatment

Posted by on Jul 30, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the impact of chemotherapy after surgery (CAS) in patients with rectal cancer who had a complete response to chemotherapy before surgery. Researchers suggested that the routine use of CAS should not be recommended in these patients. Some background Colorectal cancer is one of the most common cancer...

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Looking for participants with advanced cancer to test a new therapy

Posted by on Jul 24, 2019 in Colorectal cancer | 0 comments

In a nutshell This trial is examining the effectiveness and toxicity of COTI-2 treatment in patients with advanced cancer. The main outcomes to be measured will be cancer response to the treatment and number of side effects. This study is being conducted in Texas, US. The details Cancer resistance to therapy affects successful cancer treatment. The...

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Does lymph node yield predict survival in locally advanced rectal cancers?

Posted by on Jul 21, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the impact of lymph node yield (LNY) on the outcomes of patients with locally advanced rectal cancer. Researchers suggested that a LNY of 12 or more predict improved survival in these patients. Some background Colorectal cancer is the third most common cancer worldwide. Some patients present with locally advanced...

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Liver surgery is a safe treatment for patients with BRAF-positive colorectal cancer liver metastasis

Posted by on Jul 8, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the outcomes of patients with BRAF-positive colorectal cancer liver-metastasis (CRLM; spread to the liver) undergoing surgery. Researchers suggested that surgery is associated with improved outcomes for these patients. Some background Colorectal cancer is one of the most common cancers in the US. Around 25% of...

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Tumor surgery improves survival of patients with stage 4 colorectal cancer

Posted by on Jun 23, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the outcomes of stage 4 colorectal cancer patients who received surgery. Researchers suggested that surgery in these patients is associated with an improved 5-year survival rate. Some background Colorectal cancer is the second leading cause of death in the US. A significant number of patients presents have stage 4...

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A comparison between local and radical surgery in early rectal cancer

Posted by on Jun 20, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of local vs radical surgery in patients with rectal cancer. Researchers suggested that local surgery is associated with better outcomes in certain patients with early cancers. Some background Colorectal cancer is the third most common cancer in the US. The standard treatment options for these...

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Cetuximab improves the outcomes of previously untreated patients with metastatic colorectal cancer

Posted by on May 28, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of first-line treatment with cetuximab (Erbitux) and bevacizumab (Avastin) in advanced colorectal cancer. Researchers suggested that cetuximab is associated with better outcomes when compared to bevacizumab.    Some background Colorectal cancer is the third most common cancer worldwide....

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Searching for patients with advanced colorectal cancer to test a new T-cell treatment

Posted by on May 26, 2019 in Colorectal cancer | 0 comments

In a nutshell This phase 2 trial will investigate the effectiveness of genetically-engineered cell treatment (GECT) in advanced cancer.  The main outcome will be the response to treatment. This trial is recruiting at the National Cancer Institute, Maryland, US.  The details There are limited treatment options for advanced cancer. One...

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Looking for patients with advanced BRAF positive colorectal cancer to test an immunotherapy treatment

Posted by on May 25, 2019 in Colorectal cancer | 0 comments

In a nutshell This trial is examining the effectiveness and safety of encorafenib (Braftovi), binimetinib (Mektovi) and cetuximab (Erbitux) in patients with advanced colorectal cancer. The main outcome to be measured will be tumor response to the treatment. The details Colorectal cancer is the third most common cancer worldwide. A high number of...

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Stereotactic body radiotherapy improves treatment response in metastatic colorectal cancer

Posted by on May 16, 2019 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness of stereotactic body radiotherapy (SBRT) in metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that SBRT is associated with improved tumor response and manageable side effects. Some background Colorectal cancer is the second most commonly diagnosed cancer in...

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