In a nutshell This study reviews the value of TAS-102 in the treatment of colorectal cancer that has progressed with other therapies. Researchers suggested that TAS-102 is an important treatment option for patients with progressive colorectal cancer. Some background Colorectal cancer is the third most frequently diagnosed cancer in men and the...
Read MoreType(s) of colorectal cancer (CRC)-Adenocarcinoma of the rectum Posts on Medivizor
Lymph node ratio as a risk factor of recurrence in stage 3 colorectal cancer
In a nutshell This study investigated the prognostic role of the lymph node ratio (LNR; number of lymph node metastasis per lymph nodes removed) in stage 3 colorectal cancer following post-surgery chemotherapy. Researchers suggested that LNR is strongly associated with recurrence risk (when the cancer comes back) in these patients. Some...
Read MoreLocalized surgery outcomes in early rectal cancer
In a nutshell This study investigated the outcomes of localized surgery following chemotherapy and radiation therapy (CRT) in rectal cancer. Researchers suggested that localized surgery should only be considered after a complete response to CRT. Some background Radical surgery or total mesorectal excision (TME; bowel and lymph nodes around...
Read MoreDoes bevacizumab increase hemorrhage risk in metastatic colorectal cancer?
In a nutshell This study investigated the risk of hemorrhage (blood loss) associated with bevacizumab (Avastin) treatment in metastatic (spread to other parts of the body) colorectal cancer patients. Researchers reported that bevacizumab significantly increases the risk of hemorrhage. Some background The formation of new blood vessels is an...
Read MoreNot just for headaches: Aspirin use during pre-surgery chemoradiation in rectal cancer
In a nutshell This study investigated whether aspirin has an effect against rectal cancer during pre-surgery chemotherapy and radiation therapy (CRT). Researchers reported that the use of aspirin is associated with a better outcome and survival. Some background Pre-surgery CRT has been shown to improve the rate of local recurrences (when the...
Read MoreDoes aspirin help survival rates in colorectal cancer?
In a nutshell This study investigated the association between the use of aspirin after the diagnosis for colorectal cancer (CRC) and CRC-specific survival and overall survival. Researchers suggested that the use of aspirin after diagnosis is associated with a positive outcome. Some background Aspirin and other anti-inflammatory drugs have been...
Read MoreManagement of colorectal liver metastasis
In a nutshell This study investigated the surgical treatment and associated outcomes of colorectal liver metastasis (the cancer has spread to the liver). Researchers suggested that individualized care for each patient is crucial to better plan the treatment and extent survival. Some background The liver is the most common place for colorectal...
Read MoreImmunonutrition in colorectal patients undergoing surgery reduces complication rates
In a nutshell This study investigated the effects of immunonutrition in colorectal cancer patients undergoing surgery. Researchers reported that including immunonutrients in patient diets reduces the complications after surgery and increases survival. Some background The Enhanced Recovery After Surgery (ERAS) program describes the recommended care...
Read MoreSurvival rates and prognostic factors for sporadic colorectal cancer in young patients
In a nutshell This study investigated the survival rates and prognostic factors (future course of the cancer) for sporadic (occurs in people with no cancer family history) colorectal cancer in young patients. Researchers reported that young patients had more aggressive cancers and shorter survival rates. Some background Colorectal cancer is more...
Read MoreMalnutrition caused by pre-surgery chemotherapy is associated with rectal cancer treatment outcomes
In a nutshell This study investigated the association between malnutrition caused by pre-surgery chemotherapy and radiation (CRT) and rectal cancer treatment tolerance and anastomotic leakage (AL; leakage of intestinal fluids). Researchers reported that malnutrition related to CRT is associated with treatment tolerance and AL. Some background CRT...
Read MoreLiving beyond a diagnosis of colorectal cancer: what problems are patients faced with?
In a nutshell This study examined the treatments received and health-related quality of life of patients living with and beyond colorectal cancer. They also identified factors that were associated with poor health outcomes. Some background The numbers of patients living with or beyond the diagnosis of colorectal cancer is increasing worldwide. In...
Read MoreTen year update: improvements in colorectal cancer management
In a nutshell This article reviews the causes and management of colorectal cancer. They specifically focus on improvements that have occurred in the last ten years. Some background Colorectal cancer (CRC) is the third most common cancer worldwide and the fourth leading cause of cancer-related deaths. Risk factors include age, family history of...
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