In a nutshell This study compared the survival and safety outcomes of pembrolizumab (Keytruda; PEM) plus enzalutamide (Xtandi; ENZ) combination versus pembrolizumab alone in patients with previously untreated metastatic castration-resistant prostate cancer (mCRPC). The data showed that PEM plus ENZ combination was associated with increased survival...
Read MoreType of prostate cancer-Adenocarcinoma Posts on Medivizor
Comparing the outcomes of robot‑assisted and laparoscopic radical prostatectomy for the treatment of localized prostate cancer.
In a nutshell This study compared the outcomes of robotic-assisted radical prostatectomy (RARP) with standard laparoscopic radical prostatectomy (LRP) for the treatment of patients with localized prostate cancer. The study found that the RARP approach was associated with better outcomes compared to LRP. Some background Localized prostate cancer (PCa)...
Read MoreComparing the outcomes of Retzius-sparing versus standard robotic prostate surgery for the treatment of localized prostate cancer.
In a nutshell This study compared the outcomes of Retzius-sparing (RS) robotic-assisted laparoscopic prostatectomy (RALP) with standard RALP (sRALP) for the treatment of patients with localized prostate cancer (PCa). The study found that the RS-RALP approach may be associated with better urinary outcomes compared to sRALP. Some background...
Read MoreEvaluating the combination of sipuleucel-T with radium-223 in men with metastatic castration-resistant prostate cancer spread to the bone.
In a nutshell The study investigated the effectiveness of combining sipuleucel-T (Provenge) with radium-223 (Xofigo) therapy in men with castration-resistant prostate cancer (CRPC) that has spread to the bones. The key finding was that the combination therapy improved the survival rates of these patients. Some background Prostate cancer often...
Read MoreWhich hormonal therapy should be first in patients with castration-resistant metastatic prostate cancer?
In a nutshell This study analyzed and evaluated which hormonal therapy should be given first, abiraterone acetate (Zytiga) plus prednisone (Deltasone) (AAP) or enzalutamide (Xtandi; ENZ) in patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that AAP followed by ENZ is more effective in delaying...
Read MoreEvaluating photoselective vaporization for urinary symptoms in patients with prostate cancer on active surveillance.
In a nutshell This study aimed to investigate the safety and effectiveness of photoselective vaporization of the prostate (PVP) in patients with prostate cancer with lower urinary tract symptoms (LUTS) during active surveillance. The results suggested that PVP treatment was safe and effective in these patients. Some background Active surveillance (AS)...
Read MoreEvaluating the outcomes of salvage Retzius-sparing robotic-assisted radical prostatectomy
In a nutshell This study investigated the effectiveness and functional outcomes of using the Retzius-sparing robotic-assisted radical prostatectomy (RS-RARP) as a salvage treatment for patients with localized prostate cancer (PCa). The study found that the sRS-RARP approach was associated with good urinary and oncological outcomes in these...
Read MoreEvaluating the long-term outcomes of regional (hockey-stick) prostate cryoablation in men with low- or intermediate-risk prostate cancer
In a nutshell This study reported the long-term effectiveness and quality of life outcomes after prostate cryoablation (a process that uses extreme cold to destroy prostate tumor) treatment for patients with low and intermediate-risk prostate cancer (PCa). The data showed that the treatment had good outcomes with minimal impact on urinary and sexual...
Read MoreCan prostate surgery be safely delayed during the COVID-19 pandemic?
In a nutshell The study examined whether delaying prostate surgery affected the outcomes of patients with high-risk localized prostate cancer. The authors found that the procedure could be safely delayed in these patients for up to 6 months after initial diagnosis without higher risks of adverse outcomes. Some background Radical prostatectomy...
Read MoreEvaluating combination therapies for metastatic hormone-sensitive prostate cancer.
In a nutshell This study was carried out to look at the use of combining radiotherapy (RT), systemic therapy (ST; whole-body treatment), and androgen deprivation therapy (ADT) for prostate cancer (PC) that is hormone-sensitive and has spread. The authors concluded that ADT plus RT led to better outcomes in patients with low-volume disease. Some...
Read MoreEvaluating the effects of abiraterone acetate in combination with androgen deprivation therapy for the treatment of metastatic hormone-sensitive prostate cancer.
In a nutshell This study examined the effects of abiraterone acetate (AA; Zytiga) in combination with androgen deprivation therapy (ADT) for the treatment of metastatic hormone-sensitive prostate cancer (mHSPC). The data showed that AA and ADT combination improves the outcomes in these patients. Some background Patients with mHSPC have...
Read MoreEvaluating cabozantinib plus docetaxel and prednisone in patients with metastatic castration resistant prostate cancer
In a nutshell The study evaluated outcomes of combining cabozantinib (Cabometyx) with docetaxel (Taxotere) and prednisone (Deltasone) in treating patients with metastatic castration-resistant prostate cancer (mCRPC). The main finding was that the combination was safe and could possibly be effective in such patients. Some background Docetaxel was the...
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