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Type of prostate cancer-Adenocarcinoma Posts on Medivizor

The effects of bipolar androgen therapy in men with metastatic castration resistant prostate cancer

The effects of bipolar androgen therapy in men with metastatic castration resistant prostate cancer

Posted by on Jul 19, 2020 in Prostate cancer | 0 comments

In a nutshell The study evaluated outcomes of bipolar androgen therapy (BAT) in men with metastatic castration-resistant prostate cancer (mCRPC) who were continuing drugs targeting androgen receptors (AR). The authors found that BAT was clinically effective in such patients. Some background BAT refers to sequential injections with testosterone in men...

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Comparing the long-term effects of two intensity modulated radiation therapies in localized prostate cancer

Comparing the long-term effects of two intensity modulated radiation therapies in localized prostate cancer

Posted by on Jun 28, 2020 in Prostate cancer | 0 comments

In a nutshell The study compared the long-term effects of moderate hypofractionated intensity-modulated radiation therapy (H-IMRT) and conventionally fractionated IMRT (C-IMRT) on outcomes in patients with localized prostate cancer (PC). The authors found that H-IMRT was similarly effective compared to C-IMRT after 10 years of therapy in such...

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Should androgen-deprivation therapy be given at the same time or before radiotherapy in the treatment of localized prostate cancer?

Should androgen-deprivation therapy be given at the same time or before radiotherapy in the treatment of localized prostate cancer?

Posted by on Jun 11, 2020 in Prostate cancer | 0 comments

In a nutshell The study looked at the sequence of dose-escalated radiotherapy (RT) and androgen-deprivation therapy (ADT) in the treatment of local prostate cancer (LPCa). The study found that treatment with ADT before RT had the same outcome as treatment with ADT and RT at the same time.  Some background LPCa is a form of cancer that is...

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Abiraterone acetate and prednisone in patients with metastatic, castration‑sensitive prostate cancer

Posted by on Dec 30, 2019 in Prostate cancer | 0 comments

In a nutshell This study evaluated if the benefit of adding abiraterone acetate (Zytiga) + prednisone (Deltasone) to androgen-deprivation therapy (ADT) in treating metastatic, castration-sensitive prostate cancer (mCSPC) would be maintained in patients treated with ADT alone. This study concluded that this treatment...

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Evaluating the overall survival in patients with non-metastatic castration-resistant prostate cancer treated with apalutamide

Posted by on Oct 27, 2019 in Prostate cancer | 0 comments

In a nutshell This study investigated the effect of apalutamide (Erleada) on survival in patients with castrate-resistant prostate cancer (CRPC). This study found that apalutamide had a positive effect on the survival of these patients. Some background One treatment option for patients with prostate cancer is androgen deprivation therapy...

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Looking for patients with advanced prostate cancer to test a new treatment strategy

Posted by on Oct 24, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 2 study will investigate cryosurgical freezing (CF) and intratumoral combination immunotherapy (ITI) in advanced prostate cancer (PC). The main outcome will be the reduction in prostate specific antigen (PSA). This trial is recruiting in California and Michigan, US. The details Metastatic prostate cancer (PC) is an...

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Searching for patients with prostate cancer to test an experimental treatment before surgery

Posted by on Oct 3, 2019 in Prostate cancer | 0 comments

In a nutshell This trial is investigating the effectiveness of pembrolizumab (Keytruda) plus enzalutamide (Xtandi) in patients with prostate cancer. The primary outcome to be measured will be the absence of cancer on the prostate after it is surgically removed. This study is being conducted in Portland, OR. The details...

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Looking for patients with high-risk prostate cancer to test a combination therapy

Posted by on Aug 31, 2019 in Prostate cancer | 0 comments

In a nutshell This study aims to examine the effectiveness of niraparib (Zejula) combined with hormone therapy and radiotherapy to treat patients with high-risk prostate cancer. The main outcome to be measured will be how long patients remain cancer-free. This study is recruiting in Philadelphia, PA. The details Prostate cancer occurs mostly...

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Looking for patients with advanced prostate cancer to test a new drug

Posted by on Jul 21, 2019 in Prostate cancer | 0 comments

In a nutshell This phase 1 trial will investigate the safety of an experimental drug, XmAb22841 (XmAb), to treat advanced cancer. The main outcome will be the safety and tolerability of XmAb. This study is recruiting in Georgia and Texas, USA. The details Advanced cancer can be difficult to treat. New drugs are being developed to address this. Immune...

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