Type of leukemia-Acute Myeloid Leukemia (AML) Posts on Medivizor
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Type of leukemia-Acute Myeloid Leukemia (AML) Posts on Medivizor

Tyrosine kinase inhibitor treatment after stem-cell transplant in patients with FLT3-ITD acute myeloid leukemia 

Tyrosine kinase inhibitor treatment after stem-cell transplant in patients with FLT3-ITD acute myeloid leukemia 

Posted by on May 18, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to review existing evidence regarding the outcome of tyrosine kinase inhibitor (TKI) maintenance therapy after allogeneic stem-cell transplantation (allo-SCT) in patients with FLT3-ITD mutated (genetic abnormality) acute myeloid leukemia (AML).   This study concluded that TKI maintenance therapy after...

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Haploidentical versus matched sibling donors for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia 

Haploidentical versus matched sibling donors for allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia 

Posted by on Mar 13, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to compare outcomes for allogeneic hematopoietic stem cell transplantation (alloHSCT) using haploidentical and matched sibling donors in patients with acute myeloid leukemia (AML).  This study concluded that both donor types provided similar outcomes for these patients.   Some background Allogeneic...

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Comparing conditioning treatments for patients with acute myeloid leukemia undergoing stem cell transplant

Comparing conditioning treatments for patients with acute myeloid leukemia undergoing stem cell transplant

Posted by on Oct 28, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate two pre-transplant conditioning regimes for patients with acute myeloid leukemia.  This study concluded that total body irradiation and fludarabine (Fludara) may be a suitable reduced toxicity conditioning treatment option for these patients. Some background A conditioning...

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Second stem cell transplant using reduced intensity conditioning for leukemia or lymphoma

Second stem cell transplant using reduced intensity conditioning for leukemia or lymphoma

Posted by on Oct 25, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the outcomes of a second hematopoietic stem cell transplant (HSCT) after reduced-intensity conditioning (RIC) for patients with leukemia or lymphoma.  This study concluded that this treatment path is feasible and a good alternative for these patients.   Some background Allogenic hemopoietic...

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Total body irradiation and risk of breast cancer after transplantation in patients with leukemia-lymphoma

Total body irradiation and risk of breast cancer after transplantation in patients with leukemia-lymphoma

Posted by on Oct 3, 2020 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the association between total body irradiation and further breast cancer diagnosis in patients treated with blood or marrow transplantation for leukemia-lymphoma.  This study concluded that there is an association between the total body irradiation and an increased risk of breast cancer in...

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Combining all-trans-retinoic acid, arsenic trioxide and idarubicin for the treatment of acute promyelocytic leukemia 

Combining all-trans-retinoic acid, arsenic trioxide and idarubicin for the treatment of acute promyelocytic leukemia 

Posted by on Jul 11, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of the combination of all-trans-retinoic acid (Vesanoid), arsenic trioxide (Trisenox), and idarubicin (Idamycin) as front-line treatment for acute promyelocytic leukemia.  This study concluded that this combination is safe and effective for these...

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Impact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide

Impact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide

Posted by on Jun 21, 2020 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan).   This study concluded that cryopreservation (CP) does...

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Differentiation syndrome in patients of IDH-mutated acute myeloid leukemia treated with ivosidenib and enasidenib

Differentiation syndrome in patients of IDH-mutated acute myeloid leukemia treated with ivosidenib and enasidenib

Posted by on Jun 7, 2020 in Leukemia | 0 comments

In a nutshell The study evaluated the occurrence of differentiation syndrome (DS) in patients with IDH-mutated acute myeloid leukemia (AML) under ivosidenib (Tibsovo) and enasidenib (Idhifa) therapy. The authors found that DS is a common and adverse condition in such patients. Some background Mutations or changes in the isocitrate dehydrogenase (IDH)...

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