Type of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor

Evaluating the effectiveness and safety of busulfan plus cyclophosphamide versus total body irradiation plus cyclophosphamide for patients with adult B-cell acute lymphoblastic leukemia.

Posted by Medivizor on Mar 26, 2023 in Leukemia | 0 comments

In a nutshell This study evaluated the effectiveness and safety of busulfan (Bu; Busulfex) plus cyclophosphamide (Cy; Cytoxan) (BuCy) regimen versus total body irradiation (TBI) plus cyclophosphamide (TBI-Cy) regimen for patients with adult B-cell acute lymphoblastic leukemia (B-ALL) in first complete remission undergoing allogeneic hematopoietic...

Clofarabine-fludarabine-busulfan conditioning before hematopoietic stem cell therapy in children with acute leukemia

Posted by Medivizor on Jan 23, 2022 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the combination of clofarabine (Clolar)-fludarabine (Fludara)-busulfan (Busulfex) as a conditioning regime in hematopoietic stem cell transplant (HSCT) for children with acute leukemia. This study concluded that this combination is safe and effective in these patients. Some...

Evaluating CAR-T cell therapies for treating blood cancers

Posted by Medivizor on Oct 16, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to review the safety and effectiveness of three chimeric antigen receptor (CAR) T cell therapies, axicabtagene ciloleucel (AXI; Yescarta), tisagenlecleucel (TIS; Kymriah), and lisocabtagene maraleucel (LIS; Breyanzi), for the treatment of blood cancers. This...

Comparing outcomes of donors for a second allogenic stem cell transplant for patients with acute lymphoblastic leukemia

Posted by Medivizor on Jul 25, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to compare outcomes of donor types for a second allogeneic stem cell transplant (alloSCT) in patients with relapsed acute lymphoblastic leukemia (ALL). This study concluded that there is no major difference in overall survival between a matched unrelated donor (MUD) and a half-matched donor (HMD) in...

Inotuzumab ozogamicin with bosutinib for relapsed/refractory Philadelphia chromosome-positive ALL or lymphoid blast phase of CML

$Inotuzumab ozogamicin with bosutinib for relapsed/refractory Philadelphia chromosome-positive ALL or lymphoid blast phase of CML$

Posted by Medivizor on Jun 27, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if a combination of inotuzumab ozogamicin (InO; Besponsa) and bosutinib (Bo; Bosulif) was safe and effective in patients with relapsed/refractory (r/r) Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL) or lymphoid blast phase (BP) chronic myeloid leukemia...

Evaluating the effectiveness and safety of inotuzumab ozogamicin for patients with relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma

$Evaluating the effectiveness and safety of inotuzumab ozogamicin for patients with relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma$

Posted by Medivizor on Apr 18, 2021 in Leukemia | 0 comments

In a nutshell This study investigated the effectiveness and safety of inotuzumab ozogamicin (Besponsa; INO) in patients with relapsed/refractory (r/r) acute lymphocytic leukemia (ALL) and non-Hodgkin lymphoma (NHL). The data showed that the treatment had good effectiveness and manageable side effects for these patients. Some background A high number...

Combining venetoclax and navitoclax with chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia and lymphoblastic lymphoma

$Combining venetoclax and navitoclax with chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia and lymphoblastic lymphoma$

Posted by Medivizor on Mar 28, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of venetoclax (Venclexta) and low-dose navitoclax (ABT-263) in combination with chemotherapy in patients with relapsed/refractory (r/r) acute lymphoblastic leukemia (ALL). This study concluded that this treatment option was well tolerated and...

Reduced intensity chemotherapy for children with very low risk acute lymphoblastic leukemia

Posted by Medivizor on Feb 26, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate minimal residual disease (MRD) levels on the outcomes of children with very low-risk (VLR) acute lymphoblastic leukemia (ALL) treated with reduced intensity therapy. This study concluded that patients who had a low level of MRD had good outcomes with reduced intensity...

Total body irradiation vs chemotherapy conditioning in children with acute lymphoblastic leukemia

Posted by Medivizor on Jan 17, 2021 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if chemotherapy (CT) conditioning could replace total body irradiation (TBI) before stem cell transplant (SCT) in children with acute lymphoblastic leukemia (ALL). This study concluded that TBI in combination with CT was safer and more effective than CT conditioning alone in these...

What factors are associated with improved outcomes for patients with Philadelphia chromosome positive acute lymphoblastic leukemia undergoing allogeneic transplantation?

Posted by Medivizor on Dec 29, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate allogeneic blood or marrow transplantation (alloBMT) with post-transplant cyclophosphamide (PTCy; Cytoxan) in patients with Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia (ALL). This study concluded that patients alloBMT with PTCy in first complete remission (CR1) leads...

Tisagenlecleucel in a real world setting for patients with acute lymphoblastic leukemia and non-Hodgkin lymphoma

Posted by Medivizor on Dec 5, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the safety and effectiveness of tisagenlecleucel (TL; Kymriah) in a real-world setting as a treatment for acute lymphoblastic leukemia (ALL) and non-Hodgkin lymphoma (NHL). This study concluded that TL has similar effectiveness and improved safety in a real-world...

Total body irradiation and risk of breast cancer after transplantation in patients with leukemia-lymphoma

Posted by Medivizor on Oct 3, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the association between total body irradiation and further breast cancer diagnosis in patients treated with blood or marrow transplantation for leukemia-lymphoma. This study concluded that there is an association between the total body irradiation and an increased risk of breast cancer in certain...

Type of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor

Evaluating the effectiveness and safety of busulfan plus cyclophosphamide versus total body irradiation plus cyclophosphamide for patients with adult B-cell acute lymphoblastic leukemia.

Clofarabine-fludarabine-busulfan conditioning before hematopoietic stem cell therapy in children with acute leukemia

Evaluating CAR-T cell therapies for treating blood cancers

Comparing outcomes of donors for a second allogenic stem cell transplant for patients with acute lymphoblastic leukemia

Inotuzumab ozogamicin with bosutinib for relapsed/refractory Philadelphia chromosome-positive ALL or lymphoid blast phase of CML

Evaluating the effectiveness and safety of inotuzumab ozogamicin for patients with relapsed/refractory acute lymphoblastic leukemia and non-Hodgkin lymphoma

Combining venetoclax and navitoclax with chemotherapy in patients with relapsed/refractory acute lymphoblastic leukemia and lymphoblastic lymphoma

Reduced intensity chemotherapy for children with very low risk acute lymphoblastic leukemia

Total body irradiation vs chemotherapy conditioning in children with acute lymphoblastic leukemia

What factors are associated with improved outcomes for patients with Philadelphia chromosome positive acute lymphoblastic leukemia undergoing allogeneic transplantation?

Tisagenlecleucel in a real world setting for patients with acute lymphoblastic leukemia and non-Hodgkin lymphoma

Total body irradiation and risk of breast cancer after transplantation in patients with leukemia-lymphoma

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