Type of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor
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Type of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor

Monitoring of asparaginase treatments for childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma

Posted by on Mar 27, 2020 in Leukemia | 0 comments

In a nutshell This study aimed to investigate the activity of two types of asparaginase drugs in pediatric patients with acute lymphoblastic leukemia or non-Hodgkin lymphoma. This study concluded that this type of treatment needs close monitoring for optimal effectiveness. Some background Asparaginase (ASNase) is a drug used in the treatment of...

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The treatment of standard-risk B-cell acute lymphoblastic leukemia with intensified postinduction therapy

Posted by on Dec 29, 2019 in Leukemia | 0 comments

In a nutshell This study evaluated if the intensified postinduction therapy is safe and effective to treat children with standard-risk (SR) B-cell acute lymphoblastic leukemia (B-ALL). The study concluded that the treatment excellently impacted survival among patients, but further intensifying the therapy might be unnecessary. Some background B-ALL is...

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Evaluating measurable residual disease at myeloablative allogenic transplantation in patients with acute lymphoblastic leukemia

Posted by on Nov 28, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if measurable residual disease (MRD) before transplant in patients with acute lymphoblastic leukemia (ALL) is associated with different outcomes in patients undergoing myeloablative total body irradiation (TBI)-based and chemotherapy (CT)-based conditioning.  This study concluded that...

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The effect of uric acid levels on the outcomes of patients having an allogeneic stem cell transplant

Posted by on Nov 2, 2019 in Hodgkin's lymphoma | 0 comments

In a nutshell This study aimed to investigate the association of uric acid levels before a stem cell transplant and patient outcomes.  This study concluded that high uric acid levels before the transplant led to increased mortality. Some background Uric acid is a product of metabolic breakdown and is a normal component of urine. It...

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Searching for patients with different types of leukemia to test modified stem cell transplants donated by relatives

Posted by on Sep 20, 2019 in Leukemia | 0 comments

In a nutshell This trial is examining the effectiveness of modified stem cell transplants (SCT) donated by patient relatives, which have certain immune cells removed to prevent transplant rejection in patients with leukemia and lymphoma. The main outcome will be the maximum dose of SCT that can be given safely and is effective. This study is recruiting...

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Stem cell transplant after chimeric antigen receptor therapy in patients with acute lymphoblastic leukemia

Posted by on Aug 13, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate if stem cell transplantation (SCT) could improve the long-term prognosis of minimal residual disease negative complete remission (MRD-CR) patients with acute lymphocytic leukemia (ALL) after chimeric antigen receptor-modified (CAR) T-cell therapy.  This study concluded that this...

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Evaluating strategies to preserve fertility in cancer patients

Posted by on Jul 23, 2019 in Leukemia | 0 comments

In a nutshell This study investigated female fertility preservation (FFP) in cancer patients. They found that FFP should be discussed with all women of reproductive age undergoing cancer treatment. Some background Cancer can have many negative effects on patient health. Infertility is a particular concern for younger female patients. Pregnancy rates...

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Blood markers to measure treatment activity of L-asparaginase in acute lymphoblastic leukemia

Posted by on Jun 25, 2019 in Leukemia | 0 comments

In a nutshell This study looked at the use of blood markers to measure treatment activity of L-asparaginase in acute lymphoblastic leukemia (ALL). Researchers found that antithrombin (AT) and fibrinogen (FIB) could be used to measure effective levels of L-asparaginase in these patients.  Some background L-asparaginase is a treatment for acute...

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Infection rates in children with acute lymphoblastic leukemia who receive stem-cell transplant from unrelated donors

Posted by on Jun 5, 2019 in Leukemia | 0 comments

In a nutshell This study aimed to investigate infection rates in children with acute lymphoblastic leukemia who received stem cell transplant from unrelated donors.  This study concluded that these patients experience higher infection rates than other patients.   Some background Allogeneic hematopoietic stem cell transplantation...

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Dasatinib and chemotherapy vs stem cell transplant in the treatment of acute lymphoblastic leukemia

Posted by on May 26, 2019 in Leukemia | 0 comments

In a nutshell This study compared the outcomes after stem cell transplant (SCT) vs. dasatinib (Sprycel) combined with chemotherapy in the treatment of acute lymphoblastic leukemia (ALL) with abnormal genes. The study found that dasatinib and chemotherapy may be more effective in these patients. Some background ALL with...

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