In a nutshell This study aimed to investigate the heart function of acute lymphoblastic leukemia survivors who had been treated with anthracyclines. This study concluded that these patients had decreased heart function long after treatment. Some background Anthracyclines are a type of chemotherapy drug. Examples are daunorubicin...
Read MoreType of leukemia-Acute Lymphoblastic Leukemia (ALL) Posts on Medivizor
Long term outcomes for children with acute lymphoblastic leukemia treated with the SCMC-ALL-2009 protocol
In a nutshell This study aimed to investigate the long-term treatment outcomes and prognostic factors of acute lymphoblastic leukemia (ALL) in pediatric patients who took part in the SCMC-ALL-2009 trials. This study concluded that the long-term outcomes were favorable for these patients and better for low-risk patients...
Read MoreImpact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide
In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does not affect the outcomes of HSCT in these patients....
Read MoreImpact of graft cryopreservation on allogeneic hematopoietic stem cell transplant outcomes using post-transplant cyclophosphamide
In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does...
Read MoreEvaluating fine movement difficulties in children with acute lymphoblastic leukemia during maintenance treatment
In a nutshell This study aimed to investigate fine motor (movement) impairments in children with acute lymphoblastic leukemia who are receiving maintenance treatment. This study concluded that a high percentage of these patients experienced fine motor difficulties. Some background Treatments for...
Read MoreThe occurrence of cardiac autonomic dysfunction in patients who survived childhood acute lymphoblastic leukemia
In a nutshell The study evaluated occurrence, risk-factor, and exercise response of cardiac autonomic dysfunction (CAD) in adult survivors of childhood acute lymphoblastic leukemia (ALL). The authors found that over one-third of survivors developed CAD. It was related to lower exercise capacity. Some background Survivors of childhood ALL have reduced...
Read MoreManaging patients with leukemia during the COVID-19 pandemic
In a nutshell The report recommends several treatment modifications for patients with leukemia during the high-risk period of the COVID-19 pandemic. The main recommendations are to reduce clinic visits, use less intensive chemotherapy, and care through telemedicine for effective treatment. Some background Managing patients with leukemia during...
Read MoreMaintenance treatment impact on sleep-wake rhythms and cancer-related fatigue in children with acute lymphoblastic leukemia
In a nutshell This study aimed to investigate the impact of maintenance treatment on cancer-related fatigue and sleep-wake rhythms in pediatric patients with acute lymphoblastic leukemia. This study concluded that sleep-wake rhythms are disturbed, physical activity levels lower and cancer-related fatigue levels higher...
Read MoreThe effects of continued blinatumomab therapy in adult patients with relapsed/refractory acute lymphoblastic leukemia
In a nutshell The study evaluated treatment outcomes in patients with relapsed/refractory (R/R) acute lymphoblastic leukemia (ALL) who continued blinatumomab (Blincyto; BL) after initial therapy. The authors found that long-term BL therapy can improve survival in these patients. Some background 45% of adults with ALL experience R/R...
Read MoreDo stem cell transplants improve patients’ long-term survival?
In a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreMonitoring of asparaginase treatments for childhood acute lymphoblastic leukemia and non-Hodgkin lymphoma
In a nutshell This study aimed to investigate the activity of two types of asparaginase drugs in pediatric patients with acute lymphoblastic leukemia or non-Hodgkin lymphoma. This study concluded that this type of treatment needs close monitoring for optimal effectiveness. Some background Asparaginase (ASNase) is a drug used in the treatment of...
Read MoreThe treatment of standard-risk B-cell acute lymphoblastic leukemia with intensified postinduction therapy
In a nutshell This study evaluated if the intensified postinduction therapy is safe and effective to treat children with standard-risk (SR) B-cell acute lymphoblastic leukemia (B-ALL). The study concluded that the treatment excellently impacted survival among patients, but further intensifying the therapy might be unnecessary. Some background B-ALL is...
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