In a nutshell This study examined whether new insulin glargine 300U/ml is safe and effective in type 2 diabetics. Some background Patients with type 2 diabetes (T2D) initially produce insulin (hormone which lowers blood sugar levels) but it fails to work in the body. Drugs such as metformin (Glucophage) aim to help insulin work in the...
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A generic alternative to Lantus? The effectivness of a generic insulin glargine for type 2 diabetics
In a nutshell This study examined whether Ly 2963016 insulin glargine is safe and effective in type 2 diabetics. Some background Patients with type 2 diabetes (T2D) generally produce insulin but it fails to work in the body. T2D is a progressive disease, and over time, the pancreas reduces insulin production. T2D patients then require insulin...
Read MoreSitagliptin is safe and effective for Asian type 2 diabetes patients
In a nutshell This study examined the safety and effectiveness of the addition of sitagliptin (Januvia) to insulin therapy in Asian type 2 diabetes patients. Some background Type 2 diabetes is a progressive disease. While blood glucose (sugar) levels can often first be controlled with diet and exercise alone, patients will need to add...
Read MoreWhen long-acting insulin is no longer enough: comparing the addition of liraglutide or short-acting insulin
In a nutshell This study compared the addition of the new drug liraglutide (Victoza) to the addition of short-acting insulin in type 2 diabetics already treated with long-acting insulin and metformin. Some background Type 2 diabetes is a progressive disease. In the beginning patients may be able to control their blood glucose (sugar) with...
Read MoreInsulin therapy; can diet interventions improve weight loss?
In a nutshell This study aimed to examine the impact of dietary changes on body weight in patients taking insulin detemir (Levemir). Some background Type 2 diabetes is a long-term, progressive disease caused due to resistance to insulin. A widely used treatment option is the administration of insulin. Insulin detemir is a...
Read MoreHigh-dose dapagliflozin provides additional glycemic control in insulin-dependent type 2 diabetes
In a nutshell This study evaluated the safety and effectiveness of dapagliflozin in advanced type 2 diabetes over 2 years of treatment. Some background The sodium glucose cotransporter 2 (SGLT2) is a protein located in the kidneys which contributes to glucose uptake. Dapagliflozin (Farxiga) blocks the action of SGLT, and has been shown to reduce...
Read MoreA diabetic’s best friend
In a nutshell This study investigated the use of trained dogs, who alert owners to dangerous changes in blood glucose levels, for the prevention of hypoglycemia and anxiety among diabetic patients. Some background Dangerously low blood glucose levels, or hypoglycemia, are common events among insulin-dependent diabetic patients. Severe hypoglycemia...
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