In a nutshell This study investigated whether 3 meals a day improved blood glucose control and weight loss compared to 6 meals a day for patients with Type 2 diabetes (T2D). This study found that fewer meals a day improved blood glucose control and weight loss and reduced hunger and cravings. Some background Controlling blood sugar levels is a...
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In a nutshell This study investigated the safety and effectiveness of a combination of two different types of insulin (IDegAsp) in people with type 2 diabetes (T2D). It was determined that IDegAsp was safe and effective at controlling blood glucose levels in a variety of patients. Some background People with T2D can control their symptoms, at first,...
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In a nutshell This study investigated the effectiveness and safety of dulaglutide (Trulicity) in combination with insulin in people with type 2 diabetes (T2D). It was determined that adding dulaglutide reduced HbA1c (measures average blood glucose over the last 3 months), reduced body weight, and did not increase the risk of hypoglycemia (dangerously low...
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In a nutshell This study investigated if administering fast-acting insulin aspart (faster aspart) at mealtimes improved glycemic control in patients with type 2 diabetes. They found that faster aspart improved glycemic control compared to basal (long-lasting) insulin alone, but with increased hypoglycemia and weight gain. Some background...
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In a nutshell This study looked at the effects of IDegLira, a combination insulin drug, on outcomes in patients with uncontrolled type 2 diabetes. They found that IDegLira improved glycemic (blood sugar) control and aided weight loss in these patients. Some background The treatment of type 2 diabetes is to achieve glycemic control. This can slow...
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In a nutshell This study examined the safety and effectiveness of SGLT2 inhibitors in addition to insulin in patients with type 2 diabetes (T2D). It determined that these drugs improve glycemic control (control of blood glucose levels), but increase the risk of some side effects. Some background SGLT2 is a protein in the kidneys that is important...
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In a nutshell This study investigated the effects of insulin degludec (Tresiba) versus insulin glargine U100 (Lantus) on hypoglycemia (low blood sugar) in patients with type 2 diabetes. They found the number of hypoglycemic episodes was significantly lower in patients receiving insulin degludec. Some background Insulin therapy is a...
Read MoreIn a nutshell This study examined whether metformin can reduce the risk of mortality, cardiovascular (heart and blood vessel) events, and cancer in patients with type 2 diabetes when combined with insulin. The authors concluded that a combination of insulin and metformin reduces the mortality and cardiovascular risk. Some background Insulin...
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In a nutshell This study examined the factors which could predict insulin-associated weight gain. The authors concluded that diabetes-related distress, insulin dose and age contribute to weight gain in insulin-dependent type 2 diabetes. Some background Insulin therapy is used to reduce blood glucose (sugar) levels in patients with type 2 diabetes...
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In a nutshell This study compared the effects of two types of insulin – the currently used fast-acting insulin aspart (NovoLOG/NovoRapid) and a new faster-acting insulin aspart. The study concluded that the faster-acting insulin aspart had a faster blood glucose lowering effect. Some background In individuals without diabetes, the...
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In a nutshell The study investigated the safety and effectiveness of LY2963016 insulin glargine (LY IGlar). It was concluded that LY IGlar is as effective and well-tolerated as current standard insulin glargine (Lantus). Some background Insulin glargine is a long-acting form of insulin. Long-acting insulin is often used to provide stable blood...
Read MoreIn a nutshell This review examined the safety and effectiveness of technosphere insulin for the treatment of diabetes. The authors concluded that technosphere insulin is safe and effective in reducing blood glucose levels at meals. Some background Insulin (a hormone which reduces blood glucose levels) replacement therapy is used in the...
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