In a nutshell This study evaluated the long-term outcomes of chemotherapy plus radiotherapy for patients with early-stage classical Hodgkin's lymphoma (cHL). The authors found that this treatment combination was highly effective, with minimal late side effects. Some background Early-stage (stage 1 to 2) cHL is usually treated with a...
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MRI prognostic parameters in tailoring treatment for locally advanced rectal cancer
In a nutshell This study investigated the use of MRI predictive results to decide the best treatment for patients with locally advanced rectal cancer (LARC). Researchers suggested that early MRI results should be used in the treatment decision making. Some background Colorectal cancer is the third most common cancer in the world. Patients with LARC...
Read MoreLooking for patients with prostate cancer to test a type of radiation treatment
In a nutshell This phase 3 trial will compare the safety and effectiveness of hypofractionated radiotherapy (HF-RT) to standard radiotherapy (RT). The main outcomes will be the number of grade 2 side effects and disease control. This trial is recruiting in Houston, Texas, United States. The details Radiation therapy (RT) is a...
Read MoreConcurrent vs. sequential – which is the best chemoradiotherapy strategy for non-small cell lung cancer?
In a nutshell This study investigated if concurrent (cCRT) or sequential chemoradiotherapy (sCRT) was more effective in non-small cell lung cancer (NSCLC). They found that sCRT was associated with better survival than cCRT. Some background Non-small cell lung cancer (NSCLC) is a common cancer. It is usually diagnosed at an advanced stage. Standard...
Read MoreUltra-hypofractionated versus conventionally fractionated radiotherapy for prostate cancer
In a nutshell This study aimed to evaluate ultra-hypofractionated radiation therapy (UHFRT). This study found that UHFRT is safe and effective in the treatment of prostate cancer. Some background One option for the treatment of prostate cancer is radiation therapy. Conventional radiation treatment (CRT) involves using small doses of radiation 5...
Read MoreRadiation therapy after surgery improves survival in patients with metastatic rectal cancer
In a nutshell This study investigated the survival outcomes in patients with rectal cancer after surgery with and without radiation therapy (RT). Researchers suggested that RT after surgery is associated with improved outcomes. Some background Rectal cancer is one of the most common cancers worldwide. Between 15 to 20% of patients present metastatic...
Read MoreRisk of further cancers after radiotherapy or surgery for localized prostate cancer
In a nutshell This article investigated the risk of new primary (cancer that does not originate in another organ) cancers after treatment with carbon ion radiotherapy (CIRT), photon radiotherapy (PRT) or surgery for localized prostate cancer (PC). The authors concluded that CIRT is associated with a lower risk of new primary cancers vs...
Read MoreSearching for patients with prostate cancer to test low-dose or high-dose brachytherapy
In a nutshell This phase 3 trial is examining the effectiveness and safety of low dose rate (LDR) vs high dose rate (HDR) prostate brachytherapy (BT) for patients with prostate cancer (PC). The main outcome to be measured will be the quality of life in terms of urinary symptoms. This trial is recruiting in British Columbia,...
Read MorePatient-reported outcomes after breast-conserving treatment: what is the impact of radiotherapy?
In a nutshell This study investigated patient-reported outcomes related to radiotherapy (RT) for breast cancer. They found that patients were dissatisfied with outcomes after RT but this was not a long-term effect. Some background Breast cancer is the most common form of cancer in women. A number of strategies are used to treat BC. A lot of BC cases...
Read MoreRadiation after mastectomy in patients with breast cancer and positive lymph nodes
In a nutshell This study wanted to find out if performing radiation therapy on patients with breast cancer who have had surgery results in a lesser quality of life. The study found that the patients who had radiotherapy had a higher chance of having pain, swelling, skin problems and sensitivity in the area of the breast. Some background Breast cancer...
Read MoreA review of adolescent Hodgkin lymphoma.
In a nutshell This study reviewed how the research on pediatric and adult Hodgkin lymphoma (HL) could be applied to adolescent HL. The main finding was that treatments for pediatric and adult HL have similar effects in adolescent HL. Some background About 8500 people are diagnosed with HL in the US each year. There are 2 main types of HL:...
Read MoreLymphocyte count reduction is associated with better rectal cancer outcomes
In a nutshell This study investigated the relationship between lymphocyte (a type of white blood cells) counts and treatment outcomes for patients with rectal cancer. Researchers suggested that lymphocyte count reduction may be caused by rectal cancer treatment and is associated with better tumor response. Some background Colorectal cancer is the...
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