In a nutshell This study was carried out to assess different dosing regimens of hypofractionated stereotactic body radiotherapy (SBRT) in patients with prostate cancer. The study found that both doses were associated with high effectiveness and manageable side effects. Some background Radiotherapy is an effective treatment for early-stage PC....
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In a nutshell This study investigated the long-term side effects of low anterior surgery for rectal cancer. Researchers suggested that radiation before surgery is associated with poorer bowel function after surgery. Some background Rectal cancer is a frequent and serious disease. In the US there are 43,340 new cases of rectal cancer every...
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In a nutshell This study looked at whether the use of high-dose (HD) brachytherapy (BT) and hypofractionated external beam radiotherapy (EBRT) plus androgen-deprivation therapy (ADT) as a means of treatment for very high-risk prostate cancer (PCa). The study found that this treatment had significant benefits for patients with high-risk...
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In a nutshell The study evaluated long-term outcomes of combining hypofractionated intensity-modulated radiation therapy (H-IMRT) with prone-positioning in patients after conservation surgery for breast cancer. The authors found that this combination safely controlled cancer locally without affecting regional lymph nodes. Some background Adjuvant...
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In a nutshell This study examined if a hydrogel spacer tool improved long-term quality of life for patients with prostate cancer (PC) who received radiotherapy (RT). The results showed that the spacer significantly reduced bowel side effects and improved patients’ quality of life. Some background RT is an effective therapy for patients with...
Read MoreIn a nutshell The study looked at the effects of long term androgen deprivation therapy (LT-ADT), pelvic lymph node radiotherapy (PLNRT) and prostate bed radiotherapy (PBRT) in patients with prostate cancer and high risk of recurrence after prostate surgery. They found an increase in survival without cancer worsening in these patients. Some...
Read MoreIn a nutshell This article outlined recommended treatments for patients with Hodgkin's lymphoma (HL). Some background HL is a type of blood cancer of the lymphatic system. HL can be classified in different ways. In limited HL, cancer is found in one or two sites in the lymphatic system. In advanced HL, cancer is found on both sides of...
Read MoreIn a nutshell This study evaluated the long-term outcomes of chemotherapy plus radiotherapy for patients with early-stage classical Hodgkin's lymphoma (cHL). The authors found that this treatment combination was highly effective, with minimal late side effects. Some background Early-stage (stage 1 to 2) cHL is usually treated with a...
Read MoreIn a nutshell This study investigated the use of MRI predictive results to decide the best treatment for patients with locally advanced rectal cancer (LARC). Researchers suggested that early MRI results should be used in the treatment decision making. Some background Colorectal cancer is the third most common cancer in the world. Patients with LARC...
Read MoreIn a nutshell This phase 3 trial will compare the safety and effectiveness of hypofractionated radiotherapy (HF-RT) to standard radiotherapy (RT). The main outcomes will be the number of grade 2 side effects and disease control. This trial is recruiting in Houston, Texas, United States. The details Radiation therapy (RT) is a...
Read MoreIn a nutshell This study investigated if concurrent (cCRT) or sequential chemoradiotherapy (sCRT) was more effective in non-small cell lung cancer (NSCLC). They found that sCRT was associated with better survival than cCRT. Some background Non-small cell lung cancer (NSCLC) is a common cancer. It is usually diagnosed at an advanced stage. Standard...
Read MoreIn a nutshell This study aimed to evaluate ultra-hypofractionated radiation therapy (UHFRT). This study found that UHFRT is safe and effective in the treatment of prostate cancer. Some background One option for the treatment of prostate cancer is radiation therapy. Conventional radiation treatment (CRT) involves using small doses of radiation 5...
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