In a nutshell This article looked at the effectiveness of exercise in improving physical and mental outcomes in patients with lung cancer undergoing chemotherapy (CT). The authors found that supervised exercise improved strength, lung function, and quality of life (QoL) in these patients. Some background Lung cancer is one of the most common...
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In a nutshell This study compared the patient-reported quality of life outcomes between conventionally fractionated radiation treatment (CFRT) and ultra-hypofractionated radiation treatment (UHFRT) in patients with localized prostate cancer. The data showed that both radiotherapy techniques led to similar long-term outcomes. Some background Radiation...
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In a nutshell This study evaluated the safety and effectiveness of two chemotherapy regimens (SOX and mFOLFOX6) before surgery for rectal cancer (RC) without radiotherapy. The study found that both regimens were safe and effective in these patients. Some background RC is commonly treated with surgery to remove the tumor. Patients with...
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In a nutshell The aim of this study was to evaluate the safety of giving stereotactic radiosurgery (SRS) at the same time as other cancer treatments for patients who have brain metastasis. The study found that SRS given in combination with chemotherapy, immunotherapy, or targeted therapy was safe with low levels of side effects. Some background The...
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In a nutshell This study compared the effects of intensity-modulated radiation therapy (IMRT) with a simultaneously integrated boost (SIB) to conventional radiotherapy (CRT) with a sequential boost (SeqB) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that both radiotherapy techniques...
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In a nutshell This study examined the long-term effectiveness and safety of proton therapy for localized prostate cancer. The data showed that proton therapy has favorable outcomes in these patients. Some background Localized prostate cancer (PCa) is a form of cancer that has not spread beyond the prostate gland. PCa can be treated by...
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In a nutshell The study evaluated the timing of radiotherapy (RT) and immune-checkpoint therapy (ICT) on the outcomes of patients with brain metastasis (BrM) resulting from melanoma and non-small cell lung cancer (NSCLC). The authors found that RT and ICT given at the same time may improve response and delay recurrence in these patients. Some background...
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In a nutshell This study compared whole breast irradiation (WBI) to partial breast irradiation (PBI) following breast-conserving surgery (BCS) in patients with low-risk breast cancer. The study showed similar survival between the 2 treatments, while PBI gave better cosmetic results. Some background Patients with low-risk breast...
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In a nutshell This study compared the use of radiotherapy for prostate cancer in two areas: the prostate only, or the whole pelvis. The results showed that, for high-risk patients, radiotherapy of the whole pelvis improved patient outcomes. Some background For patients with medium or high-risk prostate cancer, the standard treatment is...
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In a nutshell This trial was carried out to assess the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) compared to whole-breast irradiation (WBI) in early-stage breast cancer (BC). The authors found that the 10-year recurrence of breast tumors was similar between the 2 methods,...
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In a nutshell This trial was carried out to examine the effectiveness of radiotherapy followed by treatment with ipilimumab (Yervoy) in men with metastatic castrate-resistant prostate cancer (mCRPC). The trial found that this treatment led to higher survival in these patients compared to radiotherapy followed by placebo. Some...
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In a nutshell This study was carried out to assess different dosing regimens of hypofractionated stereotactic body radiotherapy (SBRT) in patients with prostate cancer. The study found that both doses were associated with high effectiveness and manageable side effects. Some background Radiotherapy is an effective treatment for early-stage PC....
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