In a nutshell This study compared the effectiveness and safety of two different chemotherapies in the treatment of advanced colorectal cancer (CRC). Researchers suggested that S1-based chemotherapy is a good option for the treatment of these patients. Some background CRC is one of the most common cancers worldwide. The standard treatment is surgery...
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How does COVID-19 affect patients with cancer undergoing chemotherapy?
In a nutshell This study examined how COVID-19 infection affects patients with cancer undergoing chemotherapy and the role of other factors in COVID-19 complications. The results showed that patients with advanced age and other medical conditions had a higher risk of COVID-19 complications but chemotherapy treatment did not need to be stopped. Some...
Read MoreCan melatonin improve mental side effects of chemotherapy?
In a nutshell This study evaluated whether melatonin could improve the side effects of chemotherapy for women with breast cancer. It found that melatonin improved sleep, depression symptoms, and clear thinking during chemotherapy. Some background During treatment with chemotherapy, half of the patients with breast cancer have cognitive (related...
Read MorePreserving fertility of patients with early-stage breast cancer
In a nutshell This study looked at fertility preservation (FP) in patients with breast cancer. It found that many patients choose FP before chemotherapy and that most patients have a return of ovulation following treatment. Some background 12% of patients newly diagnosed with breast cancer are under 40 years of age. Preserving fertility is a concern...
Read MoreDoes immune cell boosting drug G-CSF reduce the effects of chemotherapy in different cancers?
In a nutshell This study examined the effects of granulocyte colony-stimulating factor (G-CSF) given as a preventative measure in patients with high- and medium-risk cancer receiving chemotherapy. The results showed that preventative G-CSF allowed more patients to complete chemotherapy treatment and lowered patients’ chances of developing secondary...
Read MoreCardiovascular effects of chemotherapy after colorectal cancer surgery
In a nutshell This study investigated the cardiovascular effects of chemotherapy after colorectal cancer (CRC) surgery. Researchers suggested that this treatment increases the stiffness of blood vessels in patients with CRC. Some background Colorectal cancer is a major cause of cancer mortality. However, the mortality rate has decreased in the...
Read MoreTreatment approaches for patients with advanced Hodgkin’s lymphoma
In a nutshell This article reviewed different treatment approaches for patients with advanced Hodgkin's lymphoma (HL). Some background HL is a type of blood cancer of the lymphatic system. HL can be classified in different ways. In limited HL, cancer is found in one or two sites in the lymphatic system. In advanced HL, cancer is found on...
Read MoreCan durvalumab improve the effectiveness of treatment for patients with SCLC?
In a nutshell This study examined the effectiveness and safety of adding durvalumab (Imfinzi) to platinum-etoposide to treat patients with small-cell lung carcinoma (SCLC). The authors found that durvalumab was well-tolerated and improved survival outcomes. Some background Small cell lung carcinoma (SCLC) is a type of lung cancer that...
Read MoreIs targeted therapy more effective than chemotherapy for patients with NSCLC?
In a nutshell This study compared the effectiveness and safety of nivolumab (Opdivo) plus ipilimumab (Yervoy) versus chemotherapy for non-small cell lung cancer (NSCLC). The authors concluded that this combination treatment improved survival outcomes more than chemotherapy. Some background Treatment for NSCLC often includes chemotherapy or...
Read MoreIs radiotherapy after chemotherapy associated with late side effects in patients with Hodgkin’s lymphoma?
In a nutshell This study evaluated the long-term outcomes of chemotherapy plus radiotherapy for patients with early-stage classical Hodgkin's lymphoma (cHL). The authors found that this treatment combination was highly effective, with minimal late side effects. Some background Early-stage (stage 1 to 2) cHL is usually treated with a...
Read MoreComparing endocrine treatment versus chemotherapy for metastatic breast cancer
In a nutshell This study compared hormone therapy and chemotherapy for the treatment of metastatic (cancer that has spread) breast cancer. The authors concluded that hormone therapy plus targeted therapy is better than chemotherapy for patients with metastatic breast cancer. Some background Different types of breast cancer have different receptors....
Read MoreEvaluating GVDex chemotherapy for patients with recurrent or persistent Hodgkin’s lymphoma
In a nutshell This study examined if GVDex is as effective and safe as GVDoxil for treating Hodgkin's lymphoma (HL) that has come back or stopped responding to treatment. The authors found that GVDex was as effective as GVDoxil, with fewer side effects. Some background For most patients with HL, primary therapy is highly effective....
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