In a nutshell This study investigated the effectiveness and safety outcomes of toripalimab (Tuoyi) in combination with chemotherapy as a first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). The data showed that toripalimab in combination with chemotherapy significantly improved overall survival and survival without cancer...
Read MoreTreatment(s) now being considered-Chemotherapy Posts on Medivizor
Comparing the frequency and severity of nerve disease with eribulin versus paclitaxel before surgery in women with breast cancer
In a nutshell The study compared the frequency and severity of neuropathy (nerve damage) eribulin (Halaven) with paclitaxel (Taxol) given before surgery in women with operable breast cancer (BC). The study found that the frequency and severity of neuropathy were reduced in patients who received eribulin than in patients who received...
Read MoreEvaluating the effectiveness and safety of adding oxaliplatin (3 months vs 6 months) to 6 months of fluoropyrimidine after surgery in patients with stage II or III colon cancer.
In a nutshell This study evaluated the effectiveness and safety of adding oxaliplatin (Eloxatin; 3 months vs 6 months) to 6 months of fluoropyrimidine therapy such as 5-Fluorouracil (Adrucil) or capecitabine (Xeloda) as adjuvant (treatment after surgery) treatment in patients with stage II or III colon cancer. The data showed that adding 3 months of...
Read MoreComparing the effectiveness of TAS-102 versus regorafenib for the treatment of patients with metastatic colorectal cancer.
In a nutshell This study compared the effectiveness of TAS-102 (Lonsurf; trifluridine-tipiracil) versus regorafenib (Stivarga) for the treatment of patients with metastatic colorectal cancer (mCRC). The data showed that TAS-102 had better oncologic outcomes than regorafenib in these patients. Some background Colorectal cancer (CRC) is one of the...
Read MoreEvaluating the long-term effectiveness and safety of adding carboplatin with or without veliparib to standard chemotherapy given before surgery in patients with triple‑negative breast cancer.
In a nutshell This study reported the long-term effectiveness and safety of adding carboplatin (Paraplatin) with or without veliparib (ABT-888) to standard chemotherapy given before surgery (neoadjuvant chemotherapy; NACT) in patients with early-stage triple-negative breast cancer (TNBC). The data showed that the addition of carboplatin to standard NACT...
Read MoreEvaluating the effectiveness of trilaciclib given before chemotherapy in patients with metastatic triple-negative breast cancer.
In a nutshell This study evaluated the effectiveness of trilaciclib (Cosela) given before gemcitabine (Gemzar) plus capecitabine (Xeloda) (GC) chemotherapy regimen in patients with metastatic triple-negative breast cancer (mTNBC). The data showed that trilaciclib given before GC chemotherapy regimen was effective and significantly improved overall...
Read MoreWhat is the best timing for chemotherapy after surgery in patients with early-stage breast cancer?
In a nutshell This study looked at the timing of chemotherapy (CT) after surgery in the treatment of early breast cancer (BC). The authors found that CT given within 31 days after surgery may improve survival in patients with triple-negative (TN) BC. Some background BC is one of the most common types of cancer found in women. There are...
Read MoreFOLFIRINOX before pre-surgery treatment can improve the outcomes of patients with rectal cancer
In a nutshell The aim of this study was to investigate FOLFIRINOX (oxaliplatin, irinotecan, leucovorin, and fluorouracil) before pre-surgery chemoradiotherapy (CRT) for patients with rectal cancer (RC). The study found that FOLFIRINOX given before CRT and surgery improved the outcomes of these patients. Some background RC can be treated with...
Read MoreComparing the effectiveness of different chemotherapy regimens after surgery in early stage breast cancer
In a nutshell This study compared the effectiveness and safety outcomes of current chemotherapy regimens for treatment in patients with early-stage breast cancer (BC). The data showed that the current treatment regimens have similar effectiveness. Some background BC is classified into different subtypes depending on the presence or...
Read MoreCan exercise improve chemotherapy symptoms in patients with lung cancer?
In a nutshell This article looked at the effectiveness of exercise in improving physical and mental outcomes in patients with lung cancer undergoing chemotherapy (CT). The authors found that supervised exercise improved strength, lung function, and quality of life (QoL) in these patients. Some background Lung cancer is one of the most common...
Read MoreIs nab-paclitaxel a better option than standard solvent-based taxanes for women with breast cancer?
In a nutshell This study explored whether nanoparticle albumin-bound (nab) paclitaxel (Abraxane) is more efficient as chemotherapy before surgery compared to solvent-based (sb) taxanes in patients with breast cancer. The authors found that nab-paclitaxel was able to improve the outcomes of these patients. Some background Breast cancer...
Read MoreWhat is the optimal duration of chemotherapy after surgery for patients with stage III colon cancer?
In a nutshell This trial looked at the length of adjuvant chemotherapy (AC; chemotherapy after surgery) for patients with stage III colon cancer. The authors found that 3 months of AC resulted in similar survival with reduced levels of toxicity, and cost compared to 6 months. Some background AC has been standard care for patients with...
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