In a nutshell This study evaluated the effectiveness and safety of nivolumab (Opdivo) plus ipilimumab (Yervoy) versus nivolumab alone given after surgery in patients with stage IV melanoma. The data showed that both nivolumab plus ipilimumab and nivolumab alone after surgery were effective compared with placebo and significantly improved survival without...
Read MoreTreatment(s) already received-None Posts on Medivizor
Evaluating the safety and effectiveness of FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of metastatic colorectal cancer
In a nutshell This study evaluated the effectiveness and safety of FOLFOXIRI (fluorouracil, leucovorin, oxaliplatin, and irinotecan) plus bevacizumab (Avastin) with or without atezolizumab (Tecentriq) on the outcomes of patients with metastatic (m) colorectal cancer (CRC). The study showed that adding atezolizumab to FOLFOXIRI plus...
Read MoreEvaluating the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected NSCLC.
In a nutshell This study evaluated the effectiveness and safety of different platinum-based chemotherapy regimens given after surgery for the treatment of early-stage resected non-small cell lung cancer (NSCLC). The authors concluded that the combination of cisplatin (Platinol)-vinorelbine (Nevelbine) improved the outcomes of these patients. Also, the...
Read MoreEvaluating the long-term effectiveness and safety of 3-month versus 6-month modified FOLFOX/CAPOX treatment after surgery in patients with stage 3 colon cancer.
In a nutshell This study evaluated the long-term effectiveness and safety of 3-month versus 6-month modified FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin) or CAPOX (capecitabine and oxaliplatin) treatment after surgery in patients with stage 3 colon cancer. The data showed that 3-month modified FOLFOX/CAPOX treatment was as effective and safe as...
Read MoreComparing the effectiveness of surgery with and without oral uracil and tegafur plus leucovorin chemotherapy for patients with stage II colon cancer.
In a nutshell This study compared the effectiveness of surgery with and without chemotherapy with uracil and tegafur (Uftoral; UFT) plus leucovorin (LV; folinic acid) in patients with stage II colon cancer. This study concluded that surgery with UFT/LV chemotherapy significantly improved survival outcomes in these patients. Some...
Read MoreComparing the overall survival rates to general life expectancy predictions after radical prostatectomy in patients with prostate cancer.
In a nutshell This study compared the overall survival rates to general life expectancy predictions after radical prostatectomy (RP; prostate removal surgery) in German patients with localized prostate cancer. The study found that low- and intermediate-risk patients treated with RP have increased overall survival rates compared to general life...
Read MoreEffects of adherence to homone therapy after surgery and radiation on the outcomes of older patients with early-stage breast cancer
In a nutshell This study aimed to investigate the effects of adherence to hormonal therapy (HT) and radiation on the outcomes of older patients with early-stage breast cancer (BC). This study concluded that the lack of adherence to HT and omitting radiation can lead to poorer outcomes for these...
Read MoreComparing 2 radiation treatments for elderly women with low-risk breast cancer
In a nutshell This article compared the outcomes of older patients with low-risk breast cancer treated with accelerated partial breast irradiation (APBI) or ultra-APBI. The authors found that both treatment methods resulted in similar outcomes and side effects in these patients. Some background Breast cancer is the most commonly diagnosed...
Read MoreEvaluating the outcomes and safety of radiotherapy after immediate breast reconstruction following breast-conserving surgery
In a nutshell This study compared the effectiveness and safety outcomes of radiotherapy (RT) after immediate autologous breast reconstruction (IABR) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that RT following IABR provided aesthetically satisfactory results with manageable side effects in these...
Read MoreDoes removal of the breast tumor improve survival in stage IV breast cancer with bone metastasis?
In a nutshell This study investigated the effects of the removal of the breast tumor in patients newly diagnosed with stage IV breast cancer and bone metastasis only. The data showed that removal of the breast tumor improved survival outcomes and decreased the recurrence rates in these patients. Some background In stage IV breast cancer (BC), the...
Read MoreWhat is the optimal duration of chemotherapy after surgery for patients with stage III colon cancer?
In a nutshell This trial looked at the length of adjuvant chemotherapy (AC; chemotherapy after surgery) for patients with stage III colon cancer. The authors found that 3 months of AC resulted in similar survival with reduced levels of toxicity, and cost compared to 6 months. Some background AC has been standard care for patients with...
Read MoreIntensity-modulated radiation therapy with simultaneously integrated boost leads to shorter treatment time with similar outcomes as conventional radiotherapy after surgery for breast cancer
In a nutshell This study compared the effects of intensity-modulated radiation therapy (IMRT) with a simultaneously integrated boost (SIB) to conventional radiotherapy (CRT) with a sequential boost (SeqB) following breast-conserving surgery (BCS) in patients with breast cancer. The data showed that both radiotherapy techniques...
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