In a nutshell This study was carried out to assess the use of radiotherapy (RT) after mastectomy (surgical removal of the breast) for triple-negative breast cancer (TNBC) that has spread to the lymph nodes. The authors found that RT after surgery was associated with improved survival in patients with larger tumors. Some background Triple-negative...
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In a nutshell This study compared 3 and 6 months of oxaliplatin (Eloxatin)-based chemotherapy in stage 2 colon cancer. Researchers suggested that the 3-month treatment might be a good and safer option for these patients. Some background Colorectal cancer is the third most common cancer diagnosed in both men and women in the US. Chemotherapy after...
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In a nutshell This study was carried out to assess the long-term safety and effectiveness of magnetic resonance imaging (MRI)-guided transurethral ultrasound ablation (TULSA) in patients with localized prostate cancer. The authors found that TULSA was safe and effective, with preserved quality of life. Some background Prostate cancer is one...
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In a nutshell This study looked at the safety and effectiveness of atezolizumab (Tecentriq) compared to platinum-based chemotherapy for the treatment of advanced lung cancer. They found that atezolizumab improved survival compared to chemotherapy in these patients. Some background Lung cancer is classified based on how the tumor cells look...
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In a nutshell This study presents updated longer-term data on recurrence-free survival (RFS) for pembrolizumab (Keytruda) after surgery for stage 3 melanoma. The study showed that pembrolizumab has a lasting and improving effect on RFS as a treatment after surgery. Some background For patients with stage 3 melanoma,...
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In a nutshell This trial was carried out to assess the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) compared to whole-breast irradiation (WBI) in early-stage breast cancer (BC). The authors found that the 10-year recurrence of breast tumors was similar between the 2 methods,...
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In a nutshell This study compared the survival rates for older patients with early-stage breast cancer (BC) receiving hormone therapy (HT), radiation (RT), both or none after breast-conserving surgery (BCS). The data showed that RT and HT in combination and RT alone may lead to higher survival expectancy than HT alone. Some...
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In a nutshell This study was carried out to assess the outcomes of pregnant women who have non-Hodgkin lymphoma (NHL). The authors concluded that treating NHL with CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone)-like regimens during pregnancy can be considered after the first trimester. Some background NHL...
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In a nutshell This trial was carried out to assess the effectiveness of azacitidine (Vidaza) in combination with venetoclax (Venclexta) for the treatment of untreated acute myeloid leukemia (AML) in older adults. The authors concluded that this combination prolonged survival and induced more remissions in these patients. Some...
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In a nutshell This trial was carried out to look at how safe and effective the addition of daratumumab (Darzalex) would be to the RVd regimen involving lenalidomide (Revlimid), bortezomib (Velcade), and dexamethasone (Decadron) in the treatment of patients with newly diagnosed multiple myeloma (MM). The...
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In a nutshell This overview discusses initial treatment options for classical Hodgkin lymphoma (cHL). Some background Classical HL is a cancer of the lymph nodes. Early-stage (stage I/II) cHL is contained to half the body, while advanced (stage III/IV) has spread to both the upper and lower halves of the body. Both early and advanced cHL have...
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In a nutshell This trial is examining the effectiveness of atezolizumab (Tecentriq) plus carboplatin (Paraplatin) and etoposide (Etopophos) with or without tiragolumab in patients with untreated extensive-stage small-cell lung cancer (ES-SCLC). The main outcomes that will be measured are progression-free survival (PFS) and overall survival...
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