In a nutshell This study examined the safety and effectiveness of combining brentuximab vedotin (Adcetris) and bendamustine (Treanda) in patients with reoccurring or unresponsive Hodgkin lymphoma (HL). The authors concluded that this regimen shows promise in HL which is difficult to treat. Some...Read More
Treatment Posts on Medivizor
In a nutshell This study analyzed the health-related quality of life (HRQOL) in patients with metastatic castration-sensitive prostate cancer (MCSPC) after treatment with apalutamide (Erleada) and androgen deprivation therapy (ADT). The study found that apalutamide plus ADT was well tolerated and improved survival compared to ADT alone in these...Read More
The role of androgen deprivation therapy plus radiotherapy in the treatment of prostate cancer after prostate surgery
In a nutshell This study compared the safety and effectiveness of short-term androgen deprivation therapy (ADT) combined with radiotherapy (RT) in patients who underwent radical prostatectomy (RP). The main finding was that the combination of ADT and RT reduced the risk of recurrence and disease progression in these patients. Some background RP is...Read More
What factors predict blood-related side effects of tyrosine kinase inhibitors in chronic myeloid leukemia?
In a nutshell This study aimed to investigate the occurrence of hematological (blood-related) side effects in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors. This study concluded that bone marrow fibrosis at diagnosis was a predictor of hematological side effects from tyrosine...Read More
In a nutshell This study aimed to investigate the effectiveness and safety of atezolizumab plus nab-paclitaxel in unresectable, locally advanced or metastatic triple-negative breast cancer. This study concluded that this combination had a benefit in patients with PD-L1 immune cell positive...Read More
In a nutshell This study evaluated the outcomes of patients with Hodgkin lymphoma (HL) after a first allogeneic hematopoietic stem cell transplant (allo-HSCT). This study concluded that allo-HSCT is promising for these patients, with low relapse rates. Some background Autologous (auto) HSCT is the usual next step for patients with HL that...Read More
In a nutshell This study evaluated the safety and effectiveness of high-dose cyclophosphamide (Cytoxan) for the treatment of relapsed or unresponsive non-Hodgkin’s lymphoma (NHL). This study concluded that high-dose cyclophosphamide was safe and effective for these patients. Some background Chemotherapy regimens remain a standard treatment...Read More
In a nutshell This study aimed to investigate ponatinib combined with conventional therapy in recurrent Philadelphia chromosome-positive central nervous system leukemia with a BCR-ABL T315I mutation after allogeneic hematopoietic stem cell transplant. This study concluded that ponatinib may be effective for these...Read More
How effective is long-term brentuximab vedotin treatment for patients with recurrent or non-responding Hodgkin’s lymphoma?
In a nutshell This study evaluated long-term treatment with brentuximab vedotin (Adcetris) for patients with Hodgkin's lymphoma (HL) that has come back or stopped responding to treatment. This study concluded that this treatment had a long-term benefit for some patients. Some background Most patients with HL respond well to initial treatment....Read More
In a nutshell This study aimed to investigate the use of ofatumumab maintenance treatment in patients with relapsed chronic lymphocytic leukemia. This study concluded that this treatment significantly prolonged progression-free survival in these patients and was well tolerated. Some background Ofatumumab (Arzerra) is a...Read More
In a nutshell This study investigated the quality of life outcomes in patients with overactive bladder (OAB) of 65 years of age or more. Researchers suggested that patients with OAB who received mirabegron (Myrbetriq) had improved quality of life. Some background OAB consists of an uncontrolled need or urge to urinate. Some people will leak urine when...Read More
In a nutshell This study investigated the short and long-term effects of physiotherapy in improving the freezing of gait in patients with Parkinson's disease. Researchers confirmed the effectiveness of physiotherapy in the treatment of these patients. Some background Parkinson's disease affects brain cells. These cells lose their...Read More