In a nutshell This study evaluated the effectiveness and safety of continuous subcutaneous foslevodopa-foscarbidopa (ABBV-951) for the treatment of motor fluctuations in patients with Parkinson’s disease (PD). The data showed that continuous subcutaneous foslevodopa-foscarbidopa significantly improved motor fluctuations in these patients. Some...
Read MoreSide effects or complications-Motor fluctuations Posts on Medivizor
Is AADC gene therapy a valuable option for patients with moderately advanced Parkinson Disease?
In a nutshell In this work, the authors studied whether VY-AADC01 (NBIb-1817) gene therapy was safe and effective in patients with moderately advanced Parkinson's disease (PD) patients with motor fluctuations. The authors showed that this treatment caused an improvement in motor function, quality of life, and a decrease in the level of...
Read MoreDoes ND0612 levodopa delivery system improve treatment of Parkinson’s disease?
In a nutshell This study evaluated the effectiveness and safety of the ND0612 delivery system of levodopa/carbidopa (Sinemet) in patients with Parkinson's disease (PD). The authors showed that the system was well-tolerated and safe and that it reduced the fluctuations of the levodopa plasma levels. Some background Parkinson's...
Read MoreHelicobacter pylori treatment improves symptoms in patients with advanced Parkinson’s disease
In a nutshell This study investigated how Helicobacter pylori (HP) infection and its treatment affect the treatment of Parkinson’s disease (PD). Researchers suggested that HP treatment improves the symptoms of patients with PD. Some background PD commonly affects older people. It affects the brain cells causing symptoms such...
Read MoreReviewing tolcapone for patients with Parkinson’s disease
In a nutshell This study reviewed the effectiveness and safety of tolcapone (Tasmar) in treating patients with Parkinson’s disease (PD). Researchers suggested that tolcapone might be a good and safe option for the treatment of these patients. Some background PD affects the brain cells which control body functions. These cells lose their...
Read MoreExtended-release levodopa treatment increases the ON time of patients with Parkinson’s disease
In a nutshell This study investigated the duration of ON time in patients with Parkinson’s disease treated with levodopa-carbidopa (LD-CD). Researchers suggested that LD-CL extended-release (ER) capsules (Rytary) increased ON time in these patients. Some background Parkinson’s disease affects brain cells. These cells lose their ability to...
Read MoreCVT-301 inhaled levodopa is as safe as standard levodopa in patients with Parkinson’s disease and off-symptoms
In a nutshell This study investigated the safety and effectiveness of CVT-301 (Inbrija) for the treatment of wearing-off symptoms in patients with Parkinson's disease. Researchers suggested that this treatment was effective in improving off periods with no significant differences in side effects compared to standard levodopa. Some background...
Read MoreSublingual apomorphine is a safe and effective treatment for off episodes in patients with Parkinson’s disease
In a nutshell This study investigated the effectiveness of sublingual apomorphine (Apokyn) in the treatment of off times in patients with Parkinson's disease. Researchers suggested that this treatment might be a safe and effective option for the treatment of these patients. Some background Parkinson's disease (PD) is the second most...
Read MoreAccordion pill (carbidopa-levodopa) is associated with reduced motor fluctuations in patients with Parkinson’s disease
In a nutshell This study investigated the effectiveness of a new carbidopa–levodopa treatment for patients with Parkinson's disease. Researchers suggested that this treatment is associated with a better control of the symptoms. Some background Nearly one million people will have Parkinson's disease (PD) in the US by 2020. This disease...
Read MoreGocovri treatment decreases dyskinesia and off times in patients with Parkinson’s disease
In a nutshell This study investigated the effectiveness of Gocovri (amantadine) in the treatment of dyskinesia (DYS) in patients with Parkinson's disease (PD). Researchers suggested that this treatment improves DYS symptoms. Some background PD affects brain cells. The abilities controlled by these cells are lost, such as muscle function and...
Read MoreIncreasing carbidopa dose together with levodopa, and entacapone treatment improves the outcomes in Parkinson’s disease
In a nutshell This study investigated whether increasing the doses of carbidopa/levodopa treatment improves the outcomes of patients with Parkinson's disease. Researchers suggested that higher doses of carbidopa together with levodopa and entacapone should be considered as an option for the treatment of patients with Parkinson's disease. Some...
Read MoreRepetitive transcranial magnetic stimulation to treat Parkinson´s symptoms
In a nutshell This study investigated the effectiveness of repetitive transcranial magnetic stimulation (rTMS) at controlling the symptoms of Parkinson´s patients. Researchers suggested that rTMS reduced the symptoms of these patients. Some background Parkinson’s is a progressive disease. Medications are the main treatment option,...
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