In a nutshell The authors assessed the safety and effectiveness of umbralisib (Ukoniq) in patients with relapsed or refractory (r/r) indolent (low-grade) non-Hodgkin lymphoma (iNHL). The study concluded that umbralisib was well tolerated and effective for patients with r/r iNHL. Some background iNHL is a slow-growing cancer of...
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In a nutshell This study compared letrozole (Femara), clomiphene (Clomid), or no ovarian stimulation for women with polycystic ovarian syndrome (PCOS). It found that letrozole led to the uterus being more receptive to an embryo, and to higher pregnancy rates. Some background Women with PCOS do not ovulate frequently or at all. Patients who want...
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In a nutshell This review looked at whether phosphodiesterase 5 (PDE5) inhibitors such as sildenafil (Viagra) can improve male fertility. It found that these medications improve sperm concentration, shape, and movement. Some background PDE5 inhibitors are the most common treatment for erectile dysfunction (ED). These medications increase the...
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In a nutshell This review looked at the effect of endometriosis surgery before in vitro fertilization (IVF). It found that surgery led to better pregnancy outcomes for patients with severe endometriosis. Some background Endometriosis is a condition in which cells from the lining of the uterus grow on the ovaries, Fallopian tubes, or other places...
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In a nutshell This study evaluated the benefit of adding hyperthermic intraperitoneal chemotherapy (HIPEC) to cytoreductive surgery (CS) for the treatment of colorectal cancer (CRC) that has spread to the peritoneum (the lining of the abdomen that covers all abdominal organs). The study found that HIPEC added to CS did not improve the outcomes of...
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In a nutshell This study investigated the safety and effectiveness of adding ublituximab (TG-1101) to ibrutinib (Imbruvica) treatment for patients with relapsed or refractory (r/r) chronic lymphocytic leukemia (CLL). The data showed that adding ublituximab to ibrutinib significantly improved the overall response rate compared to ibrutinib alone...
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In a nutshell This study evaluated whether a modern treatment approach is suitable in patients with rheumatoid arthritis (RA) that were pregnant or intended to become pregnant. The authors concluded that low disease activity (LDA) and remission are possible with a modern approach in these women. Some background RA is an inflammatory disease....
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In a nutshell This study compared several statin medications for the prevention of cardio-cerebrovascular (CCV) events such as strokes, heart attacks of death. It found that atorvastatin (Lipitor), pitavastatin (Livalo), rosuvastatin (Crestor), and simvastatin (Zocor) were all equally effective at preventing CCV events. Some background The most common...
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In a nutshell This study compared several statin medications for the prevention of cardio-cerebrovascular (CCV) events such as strokes, heart attacks of death. It found that atorvastatin (Lipitor), pitavastatin (Livalo), rosuvastatin (Crestor), and simvastatin (Zocor) were all equally effective at preventing CCV...
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In a nutshell This study compared the effectiveness of two different types of xenografts (transplant of a tissue or organ derived from an animal) in the treatment of Peyronie’s disease (PD). Researchers suggested that xenografts might be a good and safe treatment option for these patients. Some background PD is a disorder in which scar...
Read More![Comparing the activity and safety of [177Lu]Lu-PSMA-617 versus cabazitaxel in patients with metastatic castration-resistant prostate cancer](https://medivizor.com/blog/wp-content/uploads/et_temp/wapt_image_36241-19376_480x240.png)
In a nutshell This study compared the effectiveness and safety of lutetium-177 [177Lu]-PSMA-617 (177LuPSMA) versus cabazitaxel (Jevtana) for the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC). The data showed that 177LuPSMA treatment showed a higher response with fewer side effects in these patients. Some...
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In a nutshell This study investigated the effectiveness of fulvestrant (Faslodex) as a first-line treatment for postmenopausal women with estrogen receptor-positive (ER+) metastatic breast cancer (BC) in a real-world setting. The data showed that the outcomes of these patients in the real-world setting were similar to clinical trials...
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