In a nutshell This study reviewed the role of external beam radiation therapy in the treatment of prostate cancer. Some background Prostate cancer (PC) is a common and treatable cancer in men. There are many treatment options available. Treatment is usually chosen based on the risk of the cancer progressing, and patient...
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Is Aquablation an effective treatment for urinary symptoms caused by an enlarged prostate?
In a nutshell The authors analyzed the effectiveness of Aquablation compared to other treatments for patients with urinary symptoms caused by an enlarged prostate. The authors concluded that Aquablation is probably as effective as transurethral resection of the prostate (TURP) in these patients. Some background An enlarged prostate may cause...
Read MoreEvaluating palbociclib for patients with previously treated breast cancer
In a nutshell This study evaluated how well palbociclib (Ibrance) works in patients with breast cancer who received multiple lines of previous therapy. This study found that palbociclib was effective for these patients. Some background There are several different treatments for breast cancer depending on the types of...
Read MoreFurther surgery or non-surgical options for patients with remaining breast cancer after surgery
In a nutshell This study evaluated whether treating breast cancer that has not been completely removed with more surgery was more effective than non-surgical options such as chemotherapy. This study found that there was no difference in outcomes between treating with further surgery versus treating with a non-surgical option. Some...
Read MoreProstate cancer: can we predict recurrence?
In a nutshell This study examined the biochemical recurrence (BCR) of prostate cancer after minimally invasive prostate surgery. This study concluded the risk of BCR of prostate cancer decreases as the number of years after surgery without the disease increases. Some background One treatment option for patients with prostate...
Read MoreHigh dose vitamin D supplementation may be associated with improved colorectal cancer outcomes
In a nutshell This study investigated if high-dose vitamin D combined with chemotherapy improves outcomes in patients with metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that high-dose vitamin D was associated with an improved chance of survival. Some background Vitamin D is associated with the intake of...
Read MoreInitial management with aflibercept, laser photocoagulation or observation in patients with diabetic eye disease?
In a nutshell This article investigated the rate of vision loss at 2 years among eyes with center involved-diabetic macular edema (CI-DME; vision loss in people with diabetes) initially managed with aflibercept (Eylea), laser photocoagulation (LP) or observation. The authors concluded that there was no significant difference in vision loss at 2...
Read MoreIs sitagliptin added to insulin safe and effective in elderly patients with type 2 diabetes?
In a nutshell This article investigated the safety and effectiveness of sitagliptin (Januvia) in the management of type 2 diabetes (T2D) in elderly patients on insulin. The authors concluded that the addition of sitagliptin is effective and safe in all patients receiving it as add-on therapy to insulin. Some background In type 2...
Read MoreImportance of vitamin D and dietary calcium in patients with hypertension.
In a nutshell This article investigated the association between dietary calcium intake, vitamin D levels in the blood and hypertension (high blood pressure). The authors concluded that regular consumption of calcium may help prevent and treat hypertension in patients who do not have low levels of vitamin D. Some background Hypertension is blood...
Read MoreDoes chronic use of beta-blockers increase the risk of developing Parkinson’s disease?
In a nutshell This article investigated the association between chronic (long-term) exposure to beta-blockers (BBs) with an increased risk for Parkinson’s disease (PD). The authors concluded that the chronic use of BBs is associated with an increased risk for PD. Some background In PD, certain nerve cells (neurons) in the brain gradually break...
Read MoreDoes chronic use of beta-blockers increase the risk of developing Parkinson’s disease?
In a nutshell This article investigated the association between chronic (long-term) exposure to beta-blockers (BBs) with an increased risk for Parkinson’s disease (PD). The authors concluded that the chronic use of BBs is associated with an increased risk for PD. Some background In PD, certain nerve cells (neurons) in the brain...
Read MoreAbiraterone acetate plus prednisone: an evaluation of the long-term effectiveness in prostate cancer treated with hormonal therapy.
In a nutshell This study investigated if abiraterone acetate (Zytiga) and prednisone (Deltasone) added to androgen deprivation therapy (ADT) improve survival in patients with advanced prostate cancer. They found that this combination was effective at improving survival in these patients. Some background...
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