In a nutshell This study looked at the effect lixisenatide (Lyxumia, Adlyxin) has on the kidneys in patients with both type 2 diabetes (T2D) and heart disease. The main finding was that lixisenatide reduced the development of kidney disease in these patients. Some background Patients with T2D have high levels of sugar in their blood. This sugar gets...
Read MoreIn a nutshell This study investigated the outcomes of a very low-carbohydrate (ketogenic) diet versus a moderate-carbohydrate diet in adults with prediabetes or Type 2 diabetes. This study concluded that the adults on the low-carbohydrate diet had greater reductions in HbA1c levels (average blood glucose over 3 months), body weight, and medication usage...
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In a nutshell This study determined whether or not a moderate intake of wine would be overall beneficial for patients with well-controlled type 2 diabetes. The authors concluded that initiating the drinking of wine, as part of a healthy diet, modestly decreases heart-disease risk. Some background Moderate consumption of alcohol (particularly wine)...
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In a nutshell This study investigated whether semaglutide could improve the function of beta cells and glycemic control in patients with type 2 diabetes. The study concluded that once-weekly treatment with semaglutide improved beta cell function and glycemic control in these patients. Some background Beta cells are located in the pancreas and are...
Read MoreIn a nutshell This study compared the safety and effectiveness of lixisenatide (Lyxumi) and liraglutide (Victoza) in type 2 diabetes. Some background Lifestyle changes, such as changes to diet and exercise, and oral antidiabetic medications are first-line treatments for in type 2 diabetes (T2D). Sometimes, these are not enough...
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In a nutshell This study investigated the effect of a reduced calorie diet and exercise on the occurrence and/or severity of depression in overweight and obese type 2 diabetes patients. Some background Patients with diabetes are at a high risk of depression and tend to have a...
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In a nutshell This study investigated the effect of 3 different therapy combinations on the occurrence of cardiovascular disease in type 2 diabetes. Some background There are a number of types of drugs that can be used to treat diabetes. Metformin (Glucophage) decreases glucose production, and is often the first choice of treatment...
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In a nutshell This study investigated the blood sugar reduction and sid-effects associated with 4 different drug combinations in type 2 diabetes. Some background Metformin (Glucophage) decreases glucose production. It is often the first choice of treatment for type 2 diabetes. Commonly, other drugs are prescribed to be taken alongside...
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In a nutshell The aim of this study was to investigate the association of gender and various factors such as disease duration, age, blood sugar level and weight with gastroparesis in type 2 diabetes patients. Some background Some patients who have had type 2 diabetes for a long time can develop gastroparesis. Their stomach empties at an abnormally...
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In a nutshell This study examined whether physical activity is associated with improved fitness and improved blood glucose levels. Some background Physical activity and good control of blood glucose levels are known to reduce the risk of developing cardiovascular disease. Diabetics tend to have lower physical activity as physical activity can...
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In a nutshell This study examined whether diabetes is associated with an earlier menopause. Some background Menopause is a slow decline in the function of the ovaries and generally occurs in women between the age of 40 and 60. Certain factors such as smoking are known to be linked to an earlier menopause. It is believed that diabetes might have an...
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In a nutshell This study examined the safety and effectiveness of the artificial pancreas at night in type 1 diabetic patients. Some background An artificial pancreas is a system composed of an insulin pump and a continuous glucose monitor. This system is not currently used in diabetic patients as trials are still being carried out. An...
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