In a nutshell This study examined the effect of physical activity on the development and progression of kidney disease in type 1 diabetes (T1D). Some background Long-term hyperglycemia (high blood glucose levels) can result in many complications for diabetics. Diabetic nephropathy is a progressive kidney disease whereby...
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In a nutshell This trial investigated whether an artificial pancreas could automatically adjust the insulin dose when an initial insulin dose was administered based on an individual's weight. Some background A bihormonal bionic pancreas is an artificial pancreas. This system consists of a continuous glucose monitor (CGM) and an...
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In a nutshell The authors aimed to identify the prevalence of diabetic foot ulcers and the associated risk factors in diabetic patients. Some background Diabetic patients can develop foot ulcers, which may be prone to infection. A skin ulcer is where an area of the skin has broken down, revealing the underlying tissue. While often easily and...
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In a nutshell The authors analyzed the risk of influenza associated with diabetes. Some background Influenza, commonly called the ‘flu’, is a viral infection that attacks the respiratory system including the nose, throat and lungs. Chronic diseases such as diabetes can increase the risk of experiencing influenza. Indeed, adults...
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In a nutshell The authors evaluated the associations between work-related factors and the prevalence of diabetes and obesity. Some background The rise in the prevalence of diabetes is alarming and research attributes most of the increase to lifestyle factors. However, little knowledge exists about the influence of occupational (work-related)...
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In a nutshell This study evaluated the association between age of onset and glycemic control in patients with type I diabetes mellitus. Some background Type I diabetes mellitus is an autoimmune disease in which there is an ongoing destruction of beta cells (cells found in the pancreas that produce insulin). The disease is...
Read MoreIn a nutshell This review explored whether strict glycemic control can reduce the risk of cardiovascular events among diabetic patients. Some background Hyperglycemia, or high blood glucose levels, can damage both large and small blood vessels. Damage to large blood vessels significantly elevates the risk for complications such as heart attacks or...
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In a nutshell The aim of this review was to summarize the benefits and harms of several drugs commonly used for the treatment of adults with type 2 diabetes mellitus (T2DM). Some background Treatment for T2DM usually starts with diet changes and exercise because it is largely associated with obesity. Treating T2DM with medications aims to...
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In a nutshell The present study compared the effects of therapy with either Metformin or Sulfonylureas (Glyburide, Glipizide) on cardiovascular events (heart attack and stroke) or death in patients with type 2 diabetes mellitus (DM2). The main findings were that treatment with Sulfonylurea was associated with an increased risk of cardiovascular disease...
Read MoreThe present review examined the effect of various anti-diabetes medications on weight, in order to determine the best pharmacological strategy for weight management in patients with type 2 diabetes mellitus (T2DM). Analysis included cumulative results from several representative studies that investigated weight changes in response to common T2DM...
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The present review examined the effects of diabetes on the occurrence of osteoporosis (reduced bone mineral density-BMD) and fractures. Type 1 diabetes (T1DM) and type 2 diabetes (T2DM) are associated with a high risk of osteoporotic fractures but have different effects on the BMD. While in T1DM bone formation is damaged in T2DM the BMD is...
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