In a nutshell This study compared the effectiveness and safety of progestins to gonadotrophin-releasing hormone (GnRH) medications for women trying to conceive. The results showed that progestins were as effective and safe as GRH medications and could be used as a cheaper alternative. Some background For women using medical assistance to...
Read MoreOngoing treatment(s)-Ovarian stimulating drugs Posts on Medivizor
Does dehydroepiandrosterone supplementation improve ovarian stimulation in women with poor ovarian reserve?
In a nutshell This study investigated if dehydroepiandrosterone (DHEA) improves controlled ovarian stimulation (COS) in women with poor ovarian reserve (POR). They found that DHEA improved ovarian response in these women. Some background Ovarian reserve is a measurement of female fertility. It tells us of many ovarian follicles a...
Read MoreComparing hMG and FSH for high ovarian responders during intracytoplasmic sperm injection
In a nutshell This study compared human menopausal gonadotropin (hMG) to follicle-stimulating hormone (FSH) prior to intracytoplasmic sperm injection (ICSI) for patients predicted to have a strong ovarian response. It found that both types of gonadotropin hormone were effective, but that hMG had fewer side effects and miscarriages. Some background...
Read MoreDoes vitamin D increase the effectiveness of clomiphene citrate for women with PCOS?
In a nutshell This study looked at adding vitamin D for women with polycystic ovarian syndrome (PCOS) who were overweight and being treated with clomiphene citrate (Clomid). It found that vitamin D increased ovulation and pregnancy rates for these patients. Some background Polycystic ovarian syndrome (PCOS) is a common condition of women of...
Read MoreMild or conventional ovarian stimulation for women with poor ovarian response?
In a nutshell This study compared mild ovarian stimulation (OS) to conventional OS for women with a poor ovarian response (POR) who were undergoing in vitro fertilization (IVF). It found that conventional OS resulted in more embryos, but the live birth rate after IVF was the same for both types of stimulation. Some background IVF is an...
Read MoreWhat factors predict the outcome of clomiphene citrate ovarian stimulation in women with polycystic ovarian syndrome?
In a nutshell This study investigated factors affecting controlled ovarian stimulation (COS) with clomiphene citrate (CC) in women with polycystic ovary syndrome (PCOS). They found that low anti-mullerian hormone (AMH) and high endometrial thickness (EMT) are associated with higher clinical pregnancy rate (CPR) in these women. Some background...
Read MoreLow dose growth hormone for ovarian stimulation – are there improved outcomes in poor responders?
In a nutshell This study investigated the effectiveness of low dose (LD) growth hormone (GH) for controlled ovarian stimulation (COS) in poor responder (PR) patients. They found that LD-GH may improve fertility outcomes in these patients. Some background Controlled ovarian stimulation (COS) is used to help women ovulate. A combination of...
Read MoreOvarian response – what impact does this have on fertility success after IVF?
In a nutshell This study investigated if ovarian response (OR) has an effect on pregnancy outcomes in patients undergoing in vitro fertilization (IVF). They found that single embryo transfer (sET) in the blastocyst stage is preferred for all patients Some background In vitro fertilization (IVF) is a process that involves fertilizing an egg with sperm...
Read MoreA review of corifollitropin alfa in women undergoing ovarian stimulation
In a nutshell This study investigated corifollitropin alfa (CFTA; Elonva) in controlled ovarian stimulation (COS). They found that CFTA was effective in normal and poor responder patients. Some background The first step in assisted reproduction is oocyte (egg) harvest. Women undergo a procedure called controlled ovarian stimulation...
Read MoreManaging ovarian hyperstimulation syndrome (OHSS): can kisseptin reduce the risk?
In a nutshell This study investigated the effects of kisseptin on the risk of ovarian hyperstimulation syndrome (OHSS) in high-risk women undergoing fertility treatment. The authors suggested that kisseptin treatment resulted in lower rates of OHSS compared to standard treatment. Some background One of the first procedures for the...
Read MoreIs mild ovarian stimulation equally effective as conventional IVF?
In a nutshell This study investigated if mild ovarian stimulation is as effective as conventional stimulation in vitro fertilization (IVF). They found that mild ovarian stimulation provides greater safety and lower cost, in addition to comparable success rates. Some background A part of the IVF process, women undergo a procedure to harvest...
Read MoreDoes ovarian hyperstimulation syndrome have an effect on child heart function?
In a nutshell This study assessed the heart function of children born to mothers who had experienced ovarian hyperstimulation syndrome (OHSS), which is a complication of assisted reproduction procedures. The authors found that children born to women who had experienced OHSS had poorer heart function compared to other children. Some background...
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