In a nutshell This study looked at which factors can predict pregnancy following in vitro fertilization (IVF) for patients with a poor ovarian response (POR). It found that pregnancy was affected by age, body weight, ovarian reserve, and type of fertility medication. Some background For couples with infertility, IVF can greatly increase the chances of...Read More
Ongoing treatment(s)-Ovarian stimulating drugs Posts on Medivizor
In a nutshell This study compared letrozole (Femara), clomiphene (Clomid), or no ovarian stimulation for women with polycystic ovarian syndrome (PCOS). It found that letrozole led to the uterus being more receptive to an embryo, and to higher pregnancy rates. Some background Women with PCOS do not ovulate frequently or at all. Patients who want...Read More
In a nutshell This review looked at the safety of using letrozole (Femara) to promote ovulation. It found that letrozole does not increase birth defects or miscarriage. It also found that letrozole led to higher birth rates than clomiphene citrate (Clomid). Some background Infertility is a growing issue. Not ovulating regularly, or releasing an egg,...Read More
In a nutshell This review compared starting ovarian stimulation (OS) for egg collection at the conventional time early in the menstrual cycle, to starting it in the luteal phase, late in the cycle. It found that both timelines led to successful egg collection. Using two collections in one cycle may improve outcomes for patients with a poor response to...Read More
In a nutshell This study looked at the dose of gonadotropin (GN) used for ovarian stimulation during in vitro fertilization (IVF). It found that cycles with higher GN doses may have lower birth rates. Some background The first stage of the infertility treatment IVF is to stimulate the ovaries to produce multiple follicles. This is most often done...Read More
Letrozole vs. clomiphene citrate – which is more effective for ovulation induction in women with unexplained infertility?
In a nutshell This study compared clomiphene citrate (Clomid) and letrozole (Femara) for ovulation induction (OI) drugs in women with unexplained infertility. They found that letrozole was associated with lower miscarriage rates (MCRs). Some background Unexplained infertility is a leading cause of infertility. Assisted...Read More
In a nutshell This study investigated mild ovarian stimulation (OS) for in vitro fertilization (IVF) in women with poor response. They found that there was no difference in outcomes between conventional and mild OS in these women. Some background Controlled ovarian stimulation (COS) is an assisted reproductive technique (ART). It is...Read More
Controlled ovarian stimulation: how many mature oocytes are needed to produce at least 1 top quality embryo?
In a nutshell This study investigated the number of mature oocytes (eggs) needed to produce top-quality embryos (TQE). They found that at least 3 mature oocytes produced are associated with at least 1 TQE. Some background In vitro fertilization (IVF) first requires oocytes (eggs). They are retrieved by controlled ovarian stimulation (COS)....Read More
In a nutshell This study compared in vitro maturation (IVM) to double ovarian stimulation (DuoStim) for women expected to have a poor outcome from in vitro fertilization (IVF). It found that both methods increased the number of eggs compared to standard IVF, and that DuoStim may be more effective. Some background The first step of the infertility...Read More
Are progestins as effective as gonadotrophin releasing hormone medications for women trying to conceive?
In a nutshell This study compared the effectiveness and safety of progestins to gonadotrophin-releasing hormone (GnRH) medications for women trying to conceive. The results showed that progestins were as effective and safe as GRH medications and could be used as a cheaper alternative. Some background For women using medical assistance to...Read More
Does dehydroepiandrosterone supplementation improve ovarian stimulation in women with poor ovarian reserve?
In a nutshell This study investigated if dehydroepiandrosterone (DHEA) improves controlled ovarian stimulation (COS) in women with poor ovarian reserve (POR). They found that DHEA improved ovarian response in these women. Some background Ovarian reserve is a measurement of female fertility. It tells us of many ovarian follicles a...Read More
In a nutshell This study compared human menopausal gonadotropin (hMG) to follicle-stimulating hormone (FSH) prior to intracytoplasmic sperm injection (ICSI) for patients predicted to have a strong ovarian response. It found that both types of gonadotropin hormone were effective, but that hMG had fewer side effects and miscarriages. Some background...Read More