In a nutshell This study aimed to compare outcomes of allogeneic hematopoietic stem cell transplant (alloHSCT) using cryopreserved (frozen) and fresh grafts in patients with blood cancers who received post-transplant cyclophosphamide (Cytoxan). This study concluded that cryopreservation (CP) does not affect the outcomes of HSCT in these patients....
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In a nutshell This study examined how effective and safe a higher radiotherapy dose was for patients with non-Hodgkin lymphoma (NHL) undergoing stem cell transplantation (SCT). The authors found that patients who received a lower radiotherapy dose survived longer and had fewer side effects than the higher dose. Some background NHL is a cancer of...
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In a nutshell This study aimed to investigate post-transplant cyclophosphamide treatment in patients with acute myeloid leukemia. This study concluded that this treatment is safe and effective in these patients. Some background Post-transplant cyclophosphamide (PTCy) is an immune system suppressant. It can be used after...
Read MoreIn a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
Read MoreIn a nutshell This study examined the long-term survival of patients who received stem cell transplants (SCT) and compared them to the general population. The authors found that patients who received SCTs had almost the same chance of survival as the general population and identified factors that alter this chance. Some background Treatments such as...
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In a nutshell This study examined the effectiveness and safety of high-dose chemotherapy and stem cell transplants for children with lymphoma. The study showed that the combination treatment was very effective but that the dose may need to be adjusted for some patients. Some background Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) have very...
Read MoreIn a nutshell This study aimed to investigate the long-term outcomes for patients with acute myeloid leukemia who received reduced-intensity conditioning and allogeneic stem cell transplant. This study concluded that this treatment is safe and effective in these patients in the long-term. Some background One of the standard...
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In a nutshell This study aimed to investigate the outcomes of patients with acute myeloid leukemia after ex vivo T cell-depleted allogeneic hemopoietic stem cell transplant. This study concluded that the outcomes for these patients compare favorably to an unmodified transplant and that the modified transplant leads to lower rates of...
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In a nutshell This study aimed to investigate if sorafenib (Nexavar) would be a suitable maintenance agent for patients with acute myeloid leukemia who received a stem cell transplant. This study concluded that sorafenib is a safe and effective maintenance agent in these patients. Some...
Read MoreIn a nutshell This study aimed to investigate the impact of testosterone levels before a stem cell transplantation (SCT) on outcomes in male patients with acute myeloid leukemia (AML). This study concluded that testosterone levels may predict the outcomes of these patients. Some background Testosterone is a male...
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In a nutshell This study looked at the effectiveness of busulfan (Busilvex) and fludarabine (Fludara) before transplant in the treatment of older patients with acute myeloid leukemia (AML). Researchers found that this treatment was safe and effective in these patients. Some background Acute myeloid leukemia is a cancer of the bone marrow. It...
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In a nutshell This study looked at stem cell transplant and tyrosine kinase inhibitors (TKIs) in the treatment of chronic myeloid leukemia (CML). The study found that stem cell transplant is still an effective treatment in certain patients with CML. Some background CML is a cancer of the immune system. It may lead to abnormal immune cells. It is...
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