In a nutshell The aim of this study was to compare blood sugar control and weight loss in patients with type 2 diabetes (T2D) who were treated with canagliflozin compared to sitagliptin. The main finding was that patients treated with canagliflozin had better blood sugar control and greater weight loss than those treated with sitagliptin. Some...
Read MoreIn a nutshell The aim of this study was to investigate the relationship between the use of incretin-based anti-diabetic drugs and the risk of hospitalization due to heart failure. The main finding of the study was that the use of these drugs is not associated with an increased risk of hospitalization due to heart failure. Some background There...
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In a nutshell This study aimed to compare the effects of continuing versus stopping sitagliptin (Januvia) when starting insulin glargine (Lantus) therapy in patients with type 2 diabetes. The main finding of the study was that those who continued sitagliptin after starting insulin glargine had better blood glucose control without an increase in side...
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In a nutshell This study assessed whether patients with uncontrolled diabetes would benefit from adding ertugliflozin to their treatment regime. The authors concluded that ertugliflozin improved blood sugar control among those unable to do so with the combination of metformin (Glucophage) and sitagliptin (Januvia) alone. Some...
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In a nutshell The authors evaluated the risk of autoimmune disease development in patients starting a dipeptidyl peptidase inhibitor for type 2 diabetes. Some background Dipeptidyl peptidase-4 (DPP4) is a protein that plays a major role in glucose metabolism. DPP4-inhbitors such as linagliptin (Tradjenta), saxagliptin (Onglyza) and sitagliptin...
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In a nutshell This trial investigated the safety and efficacy of combined therapy with sitagliptin (Januvia) and pioglitazone (Actos) in type 2 diabetes mellitus (T2DM). Some background T2DM is a condition in which the cells of the body are failing to use insulin properly (insulin resistance), resulting in high blood sugar levels. Therefore, T2DM...
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