In a nutshell This study compared the effects of adding insulin glargine treatment to metformin (Glucophage), glimepiride (Amaryl) or their combination in patients with uncontrolled type 2 diabetes mellitus. Some background Hyperglycemia (high blood glucose) in type 2 diabetes mellitus arises from a combination...
Read MoreIn a nutshell This study evaluated the efficacy and safety of canakinumab on improving glucose control in metformin treated patients with type 2 diabetes. Some background Type II diabetes is a metabolic disease characterized by elevated blood sugar level (hyperglycemia) and low sensitivity to insulin (a hormone that reduces blood sugar...
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In a nutshell This trial evaluated the efficacy of dapagliflozin (Forxiga) in patients with type 2 diabetes mellitus (T2DM) uncontrolled with sitagliptin (Januvia), with or without metformin (Glucophage). Some background T2DM is a condition in which the cells of the body are failing to use insulin properly (insulin resistance), resulting in...
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In a nutshell In this study researchers examined the effect of a new drug, AZD1656, and its ability to control blood sugar levels in type 2 diabetic (T2D) patients. Some background Many different drugs, such as metformin (glucophage), are used to control blood sugar levels in T2D patients. However, not all patients manage to properly control their...
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In a nutshell This study assessed the efficacy and safety of adding gemigliptin versus sitagliptin to metformin treatment in patients with type 2 diabetes mellitus (T2DM). Some background T2DM is a condition in which patients have high blood glucose levels (hyperglycemia) when cells fail to respond to the normal actions of the hormone insulin or...
Read MoreIn a nutshell This study compared the efficacy and safety of exenatide versus glimepiride in achieving glycaemic (blood sugar) control in patients with type 2 diabetes mellitus (T2DM) uncontrolled by metformin. Some background T2DM is a condition in which patients have high blood sugar levels (hyperglycemia). Metformin (Glucophage) is the...
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