In a nutshell This trial aims to determine how effective stem cell therapy is for ovarian function among women with premature ovarian failure. The main outcome to be investigated is pregnancy rate and restart of menstruation. The trial is recruiting in Augusta (Georgia), United States The details Premature ovarian failure is a loss of normal...
Read MoreMale / female infertility-Female Posts on Medivizor
Effect of endometrioma on IVF
In a nutshell This paper studied how endometriosis and surgery can affect outcomes in women undergoing in-vitro fertilization (IVF). Based on current evidence, individualized care should be given to patients. Some background Endometriosis is a condition where the inner tissue of the uterus (endometrium), grows in other places. Endometrial...
Read MoreAnti-mullerian hormone levels can help predict outcome of in-vitro maturation treatment
In a nutshell This paper studied whether anti-mullerian hormone levels can predict outcomes of in-vitro maturation in women with PCOS. Authors concluded that in-vitro maturation could be considered in women with high levels of anti-mullerian hormone. Some background Polycystic ovarian syndrome (PCOS) is a condition where many cysts grow in the...
Read MoreCan hormone levels early in the cycle predict success of IUI or IVF?
In a nutshell This study examined whether follicle stimulating hormone and estradiol levels affected live birth rates after assisted reproduction methods. This study determined that women who initiated infertility treatment with high levels of follicle stimulating hormone (FSH) and estradiol levels were unlikely to achieve live birth through...
Read MoreExamining the timing and administration of GnRH antagonists during IVF
In a nutshell This study examined the timing of gonadotropin-releasing hormone (GnRH) antagonists during in vitro fertilization (IVF) treatments. Authors concluded that a modified early GnRH protocol achieves similar outcomes to the GnRH agonist protocol with a shorter overall treatment duration. Some background IVF is a complex process which...
Read MoreAn overview of treatment options for inducing ovulation in polycystic ovary syndrome
In a nutshell This review analyzed current evidence on the most effective approach to achieve mono-ovulation (one egg released) or ovulation in general in women with polycystic ovary syndrome (PCOS). Authors reported good safety and effectiveness for a number of treatment options for PCOS. These should be individualized wherever possible. Some...
Read MoreEarly results from uterus transplantation: 1 year on
In a nutshell This study examined clinical outcomes of uterus transplantation in 7 women with absolute uterine factor infertility (AUFI). Researchers reported continued menstruation and blood flow to the uterus 1 year after uterus transplantation. Any rejection episodes were detectable early on and treated successfully. Some background...
Read MoreLuteinizing hormone supplements and ovarian stimulation: Timing is everything?
In a nutshell This study looked at the potential benefit of introducing luteinizing hormone (LH) earlier during ovarian stimulation in older women. Starting LH on the earlier date was shown to increase clinical pregnancy rates. Some background There is an increased number of older women (over 35) seeking help to get pregnant. Success rates usually...
Read MoreCan comprehensive chromosome screening enhance IVF/ICSI success?
In a nutshell This study examined whether comprehensive chromosome screening can improve IVF/ICSI outcomes. Some background Chromosomes are structures located in each cell of the body and consist of DNA. Most cells in the human body have 23 pairs of chromosomes (46 chromosomes in total). Alterations in the number of chromosomes can...
Read MoreThe effect of high intensity exercise on polycystic ovarian syndrome
In a nutshell This study examined whether high intensity exercise could improve the cardiometabolic profile in women with polycystic ovary syndrome. Some background Polycystic ovarian syndrome (PCOS) is associated with many hormonal and metabolic (how the body breaks down and uses energy from food) factors. In addition to having fertility problems...
Read MoreBemfola: a safe and effective alternative to Gonal-f for IVF
In a nutshell This study examined whether bemfola has a similar safety and effectiveness profile as Gonal-f in women undergoing assisted reproductive technology. Some background Follicle-stimulating hormone (FSH) is a female hormone which is involved in the development of eggs in the ovaries. Gonal-f (follitropin alfa) is a drug which acts in...
Read MoreHow do on and off-label female infertility medications compare?
In a nutshell This article reviewed on and off-label drug use in female infertility treatment. Some background Female infertility affects millions of couples worldwide with many medications available to assist conception. Fertility treatments undergo assessment by the Food and Drug Administration (FDA) to gain a license for a particular...
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