While smoking remains the primary cause of lung cancer, 10 – 20% of people who develop non-small cell lung cancer (NSCLC) never smoked. NSCLC in non-smokers happens more often to women, and at an earlier age, than it does in smokers. What would cause cancer to develop without smoking? [1] One theory is that environmental factors,...
Read Morelung cancer mutations Posts on Medivizor
Biomarkers, Combination Therapy, and Lung Cancer
KRAS, one gene present in some cancers, was considered “undruggable” for years.[1] Mutated KRAS is an important target for patients with non-small cell lung cancer (NSCLC) because it’s present in 20-25% of cases.[2] Finally, one drug, sotorasib (Lumakras), is approved to treat one mutant form of KRAS gene, KRAS G12C.[3] This mutation appears in...
Read More