In a nutshell This study investigated the effect of chemotherapy drug dose on the survival outcomes of stage 3 colon cancer patients. Some background Relative dose intensity (RDI) refers to the proportion of the standard drug dose received during chemotherapy. Previous studies have shown that an RDI greater than 70% is associated with better...
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Melanoma with liver metastasis: a review on treatment options
In a nutshell The authors reviewed different treatment options available for melanoma patients with cancer spread to the liver. Some background In advanced melanoma (stages 3 and 4), cancer has spreads from the skin to other parts of the body. This is known as metastasis. Treatment of liver metastasis in advanced melanoma still remains a...
Read MoreThe relationship between low blood glucose levels and dementia in the elderly
In a nutshell This review examined the findings from studies which looked at the connection between low blood glucose levels and brain function. Some background Diabetics who experience hypoglycemia (dangerously low blood sugar levels) may have a higher risk of experiencing dementia. Dementia is a group of brain disorders, including...
Read MoreComparison of rituximab and TNF inhibitors in rheumatoid arthritis
In a nutshell The authors aimed to compare the effectiveness of rituximab (Rituxan) with a tumor necrosis factor inhibitor in the treatment of rheumatoid arthritis. Some background In rheumatoid arthritis (RA), the immune system begins attacking healthy tissue the way it normally attacks viruses or bacteria. This can cause...
Read MoreLooking for patients with advanced melanoma to test a vaccine therapy
In a nutshell This phase 1 clinical trial recruiting in Buffalo, New York aims to evaluate the side effects and best dose of a vaccine therapy for patients with advanced (stage III/IV) melanoma that has spread from the skin to other parts of the body. The primary outcome to be investigated is the maximum tolerated dose (MTD) and treatment-related...
Read MorePossible new treatment for metastatic breast cancer
In a nutshell The authors aimed to determine the effectiveness and safety adding bevacizumab (Avastin) to a chemotherapy regimen in previously treated patients with metastatic (spread to other areas of the body) breast cancer. Some background Metastasis is the spread of cancer to other organs in the body. Patients with metastatic...
Read MoreEffect of skin injection of interleukin-2 in advanced skin melanoma
In a nutshell The authors analyzed the effect of combination treatment with inerleukin-2 (Proleukin) injected in skin, with imiquimod (Zyclara) ointment in advanced skin cancer. Some background In advanced skin melanoma (stage III/IV), cancer spreads rapidly from the skin to the surrounding lymph nodes and the lymphatic channels (important part of...
Read MoreEffect of tofacitinib in synovial response of rheumatoid arthritis patients
In a nutshell The authors analyzed the effect of tofacitinib (Xeljanz) in controlling inflammation of the synovium (joint lining) in rheumatoid arthritis (RA). Some background In RA, the immune system begins attacking healthy tissue the way it normally attacks viruses or bacteria. This can cause inflammation, leading to chronic...
Read MoreDr. David Ross Camidge: Lung Cancer Patients Should “Rediscover the Feeling of Hope” (VIDEO)
Recorded on September 7, 2015 David Ross Camidge, MD, PhD Professor of Medicine, Division of Medical Oncology Director, Thoracic Oncology Clinical and Clinical Research Programs University of Colorado Denver Andrew Schorr: Hello and welcome. I'm Andrew Schorr on location in Denver, Colorado, at the World...
Read MoreIs It Possible to Test Disease Progression in Melanoma? (VIDEO)
Latest Technology Analyzes Disease Progression from Patient Power on Vimeo. Recorded on March 28, 2015 Mark Gimbel, MD Surgical Oncologist Banner MD Anderson Cancer Center Michael Wong, MD, PhD Head – Solid Tumors Section, Skin Cancer and Melanoma Clinics USC Norris Comprehensive Cancer Center Carol...
Read MoreWhen Should Prostate Cancer Patients Consider Participating in a Clinical Trial? (VIDEO)
Recorded on July 12, 2015 Sumit K. Subudhi, MD, PhD Assistant Professor, Department of Genitourinary Medical Oncology, Division of Cancer Medicine The University of Texas MD Anderson Cancer Center Jeri Kim, MD Associate Professor, Department of Genitourinary Medical Oncology, Division of Cancer Medicine The University of...
Read MoreIs there a link between pregnancy complications and death from heart disease?
In a nutshell This paper studied whether pregnancy complications could predict the risk of death from cardiovascular disease (heart or blood vessel related diseases). Some background Complications sometimes occur in pregnancy. These complications can give an indication about the mothers’ health and ability to cope with pregnancy....
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