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Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Clarithromycin administered daily reduces the skin-related side effects associated with panitumumab treatment for metastatic colorectal cancer.

Posted by on Sep 5, 2021 in Colorectal cancer | 0 comments

In a nutshell This study investigated the effectiveness and safety of preventative antibiotic treatment with clarithromycin (Biaxin) to prevent skin-related side effects associated with panitumumab (Vectibix) treatment for patients with metastatic colorectal cancer (mCRC). The data showed that clarithromycin administered daily along with a simple...

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Tucatinib plus trastuzumab and capecitabine preserves health-related quality of life in patients with metastatic HER2-positive breast cancer.

Tucatinib plus trastuzumab and capecitabine preserves health-related quality of life in patients with metastatic HER2-positive breast cancer.

Posted by on Sep 5, 2021 in Breast cancer | 0 comments

In a nutshell This study evaluated the impact of tucatinib (Tukysa) in combination with trastuzumab (Herceptin) and capecitabine (Xeloda) on health-related quality of life (HR-QoL) in patients with metastatic human epidermal growth factor (HER2)-positive breast cancer (BC). The data showed that this combination preserved HR-QoL in these patients. Some...

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Do blood pressure medications help to improve signs of brain small vessel disease?

Do blood pressure medications help to improve signs of brain small vessel disease?

Posted by on Sep 5, 2021 in Hypertension | 0 comments

In a nutshell This study looked at the effect of blood pressure (BP)-lowering medications on cerebral small vessel disease (CVSD). It found that maintaining systolic blood pressure (SBP; BP when the heart beats) between 110-129 mmHg reduced the progression of white matter hyperdensities, one of the signs of CVSD on brain scans. Some background...

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Does canagliflozin reduce the risk of hospitalization in patients with type 2 diabetes?

Does canagliflozin reduce the risk of hospitalization in patients with type 2 diabetes?

Posted by on Sep 5, 2021 in Diabetes mellitus | 0 comments

In a nutshell This study looked at the effect of canagliflozin (Invokana) on hospitalization occurrence in patients with type 2 diabetes (T2D). It found that patients treated with canagliflozin were less likely to be admitted to the hospital than patients treated with placebo.  Some background Canagliflozin is a medication...

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Will changing to a Mediterranean diet improve cholesterol in patients with coronary heart disease?

Will changing to a Mediterranean diet improve cholesterol in patients with coronary heart disease?

Posted by on Sep 5, 2021 in Coronary artery disease | 0 comments

In a nutshell This study compared the Mediterranean diet (MD) with the low-fat diet (LFD) in patients with coronary artery disease (CAD). It found that after 3 months the MD was associated with higher omega-3 levels than the LFD. Some background Cholesterol is the name commonly used for the fats in the blood. Cholesterol can block the...

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Does radiotherapy increase the risk of heart disease in patients with Hodgkin lymphoma?

Does radiotherapy increase the risk of heart disease in patients with Hodgkin lymphoma?

Posted by on Sep 5, 2021 in Hodgkin's lymphoma | 0 comments

In a nutshell This study looked at the 30-year risk of heart disease in patients with Hodgkin lymphoma (HL) treated with radiotherapy. It found that radiotherapy led to a small increase in the risk of death from heart disease or stroke in these patients.  Some background HL is often treated with a combination of chemotherapy and...

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Is closed-loop glucose control an effective treatment for patients with type 2 diabetes with serious kidney disease?

Is closed-loop glucose control an effective treatment for patients with type 2 diabetes with serious kidney disease?

Posted by on Sep 5, 2021 in Diabetes mellitus | 0 comments

In a nutshell This study looked at the use of closed-loop glucose control treatment for patients with type 2 diabetes (T2D) requiring dialysis. It found that compared to standard insulin therapy, closed-loop glucose control led to improved glucose control in these patients.  Some background Closed-loop glucose control is a form of insulin...

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Evaluating the effectiveness and safety of triple combination therapy with immunotherapy and targeted therapy for patients with advanced-stage melanoma.

Evaluating the effectiveness and safety of triple combination therapy with immunotherapy and targeted therapy for patients with advanced-stage melanoma.

Posted by on Sep 5, 2021 in Melanoma | 0 comments

In a nutshell This study evaluated the effectiveness and safety of triple combination therapy with immune and targeted therapies in patients with stage III-IV melanoma. The data showed that triple combination therapy was associated with increased survival benefits with manageable side effects for these patients. Some background Melanoma is an...

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Evaluating the impact of brain metastasis in the effectiveness of immunotherapy in patients with non-small cell lung cancer

Evaluating the impact of brain metastasis in the effectiveness of immunotherapy in patients with non-small cell lung cancer

Posted by on Sep 5, 2021 in Lung cancer | 0 comments

In a nutshell This study evaluated the effectiveness of immune checkpoint inhibitors (ICI) versus chemotherapy in patients with non-small cell lung cancer (NSCLC) andy brain metastases (BM). The data showed that the effectiveness of ICIs was similar in patients with no BM symptoms and/or treated BMs. For patients with BMs, ICI combination therapy was...

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