KRAS, one gene present in some cancers, was considered “undruggable” for years.[1] Mutated KRAS is an important target for patients with non-small cell lung cancer (NSCLC) because it’s present in 20-25% of cases.[2] Finally, one drug, sotorasib (Lumakras), is approved to treat one mutant form of KRAS gene, KRAS G12C.[3] This mutation appears in...
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Nobel Prize in Medicine, Dr. James Allison and “Hope”
At a press briefing at the International Cancer Immunotherapy Conference in New York, held October 1 just after receiving notification from the Nobel committee, Dr. James Allison said that the prize “should give patients hope because we’ve got things that we know work. If this didn’t work, there would have been no prize.” This “work”...
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