In a nutshell This study compared the effectiveness and safety of a combination of insulin glargine (Lantus) and lixisenatide (Lyxumia), called iGlarLixi, to either drug on its own, in people with type 2 diabetes (T2D). It was determined that iGlarLixi was more effective in reducing HbA1c, and did not increase the risk of side effects. Some background...
Read MoreDiabetes medication(s)-Non-insulin oral drugs Posts on Medivizor
How safe and effective is ertugliflozin in patients with poorly controlled type 2 diabetes?
In a nutshell This study determined the safety and effectiveness of ertugliflozin (Steglatro) as a single therapy for adults with poorly controlled type 2 diabetes despite diet and exercise. This study concluded that 1 year of ertugliflozin improved glycemic (blood sugar) control and reduced body weight and blood pressure, but increased genital...
Read MoreIs IDegLira a suitable treatment for patients with uncontrolled type 2 diabetes?
In a nutshell This study investigated the suitability of IDegLira for treating patients with uncontrolled type 2 diabetes. The authors concluded that using IDegLira was safe and effective at reducing blood-sugar levels. Some background IDegLira is an injectable, fixed-ratio combination of basal insulin (degludec) and a glucagon-like peptide-1...
Read MoreComparing the effectiveness of the three long-acting GLP-1RAs
In a nutshell This study compared the effectiveness of the three long-acting GLP-1RAs: once-weekly exenatide (Byetta), dulaglutide (Trulicity), and albiglutide (Tanzeum). The authors concluded that after six months all three treatments equally reduced HbA1c. Some background Glucagon-like peptide-1 receptor agonists...
Read MoreCan early control of blood sugar levels reduce the risk of heart disease?
In a nutshell This study investigated whether early control of blood sugar levels reduced the risk of developing heart disease. The authors concluded that those who managed to control their blood-sugar early were less likely to develop heart disease. Some background Patients with type 2 diabetes are advised to control blood sugar levels as...
Read MoreSafety of empagliflozin in type 2 diabetes
In a nutshell This study investigated the safety of empagliflozin (Jardiance) in patients with type 2 diabetes (T2D). It was determined that empagliflozin is a safe drug, but may increase the risk of genital infections. Some background Empagliflozin is an SGLT2 inhibitor. SGLT2 is a protein in the kidneys that is important in controlling blood...
Read MoreDo blood sugar medications increase heart attack risk in patients with diabetes receiving dialysis for kidney disease?
In a nutshell This study investigated if medications used to treat high blood sugar increased the risk of heart attack in patients with diabetes and end-stage kidney disease undergoing dialysis. This study concluded that patients taking non-insulin drugs were more likely to have a heart attack. Some background Diabetes is an illness that...
Read MoreIs insulin degludec more effective than insulin glargine U100 at reducing hypoglycemia in patients with type 2 diabetes?
In a nutshell This study investigated the effects of insulin degludec (Tresiba) versus insulin glargine U100 (Lantus) on hypoglycemia (low blood sugar) in patients with type 2 diabetes. They found the number of hypoglycemic episodes was significantly lower in patients receiving insulin degludec. Some background Insulin therapy is a...
Read MoreDoes omega-3 fatty acid supplementation affect kidney function in type 2 diabetes?
In a nutshell This study examined if Omega-3 fatty acid supplementation could improve kidney function in patients with diabetes and hypertriglyceridemia. They found that a daily dose of 4 grams of Omega-3 fatty acids improved kidney function in these diabetic patients. Some background A common complication of diabetes is kidney disease. If it is...
Read MoreThe effects of age, gender and BMI on outcomes with insulin treatment
In a nutshell This study analyzed the impact of certain patient characteristics on outcomes with insulin treatment for type 2 diabetes. Authors reported significant effects of age, gender, and body weight. Female patients and those in a normal weight category are less likely to achieve treatment goals and may require more clinical attention. Some...
Read MoreAre vildaglipton and insulin used together better for treating type 2 diabetes?
In a nutshell This study examined whether vildagliptin (Galvus) added to insulin treatment was safe and effective over the long term. The study concluded that vildagliptin in addition to insulin was effective and well tolerated by type 2 diabetes patients. Some background Patients with type 2 diabetes...
Read MoreGemigliptin effective as part of combination drug therapy in type 2 diabetes
In a nutshell This study examined the impact of gemigliptin as part of a combination with metformin (Glucophage) and glimepiride (Amaryl) in patients with type 2 diabetes (T2D). The study found that gemigliptin was effective in the management of T2D in combination with metformin and glimepiride. Some background...
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