In a nutshell This study investigated the effectiveness and safety of short 15-minute panitumumab (Vectibix) injections. Researchers suggested that these injections were well tolerated with manageable side effects. Some background Panitumumab is a therapy that targets the EFGR receptor on cancer cells. This blocks cell growth which results in cell...
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In a nutshell This study reviewed other studies about different treatments for metastatic (spread to other parts of the body) melanoma. Researchers suggested that targeted therapy improves overall survival of these patients when compared to chemotherapy. Some background Melanoma is the most dangerous common skin cancer. 70 to 80% of patients are...
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In a nutshell This study aimed to discover if docetaxel (Taxotere) added to androgen-deprivation therapy (ADT) increases overall survival for patients with metastatic hormone-sensitive prostate cancer. This study found that overall survival was higher for patients who received ADT and docetaxel compared to those who took ADT. Some...
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In a nutshell This study examined the side effects and health related quality of life (HRQL) of advanced melanoma patients treated with cobimetinib (Cotellic) plus vemurafenib (Zelboraf). Researchers suggested that these patients maintained their HRQL when compared with patients treated with vemurafenib alone. Some background Prior studies...
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In a nutshell This study investigated the effect of physical exercise in metastatic (spread to other parts of the body) colorectal cancer (mCRC). Researchers suggested that physical exercise increases patient quality of life. Some background The overall survival of patients with mCRC has improved during the last two decades. This was mainly due to new...
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In a nutshell This study investigated the effectiveness of fluoropyrimidine and irinotecan (FLIRI) to treat metastatic (spread to other parts of the body) colorectal cancer. Researchers suggested that FLIRI could be used as first line treatment for these patients. Some background The chemotherapy combinations FOLFOX, CapeOX or FOLFIRI plus...
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In a nutshell This study summarized the effectiveness of gefitinib for treating advanced non-small-cell lung cancer. The authors concluded that gefitinib may be beneficial for prolonging time until progression and quality of life, particularly for patients with the specific genetic mutation EGFR. Some background Cancers can be caused by specific...
Read MoreIn a nutshell This study aimed to examine the effectiveness and safety of enzalutamide (Xtandi) compared to bicalutamide (Casodex) in castration-resistant metastatic prostate cancer (cancer that does not respond to hormone therapy) patients in different age groups. This study concluded that enzalutamide improved outcomes for...
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In a nutshell This trial is examining the effectiveness of nivolumab (Opdivo) in combination with cabozantinib (Cometriq) for metastatic triple-negative breast cancer (cancer that is not dependent on hormones or HER2 for growth). The outcome to be measured will be the response rate of the cancer to this treatment. This study is...
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In a nutshell This trial is examining the effectiveness of the antibody-drug conjugate SYD985 for HER2-positive inoperable advanced breast cancer. The main outcome to be measured will be time from treatment until disease progression or the time taken for tumor growth or spread. This study is being conducted in Baltimore, Maryland, inthe United...
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In a nutshell This phase 2 trial aims to test the safety and effectiveness of the combined treatment with pembrolizumab (Keytruda), trametinib (Mekinist) and dabrafenib (Tafinlar) for advanced melanoma. The main outcomes of this trial include overall survival (time from treatment until death from any cause), side effects and response rate to the...
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In a nutshell This study investigated the effectiveness of the chemotherapy FOLFOXIRI as treatment for colorectal cancer. Researchers suggested that this chemotherapy is associated with improved treatment outcomes. Some background Chemotherapy is used in cancer patients to reduce symptoms and prolong survival. Chemotherapy drugs attack cancer...
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