In a nutshell This phase I/II trial aims to determine the safety of administering shorter courses of radiation over a shorter period of time to patients who have had their prostate removed. The main outcome to be investigated is dose safety and toxicity in patients and to determine quality of life benefits. The details Radiation therapy...
Read MoreCurrent stage -Stage III Posts on Medivizor
The effect of standard treatments in patients with favorable and unfavorable prostate cancer
In a nutshell The authors aimed to determine the effect of common treatments on prostate cancer-specific mortality for patients with intermediate-risk prostate cancer. Some background Intermediate-risk prostate cancer is cancer that has grown through and/or out of the prostate. It can be further classified as favorable or...
Read MoreIdentifying prostate cancer progression
In a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
Read MoreThe complications associated with hormone therapy in advanced prostate cancer
In a nutshell The authors aimed to determine the complications of hormone therapy in patients with advanced prostate cancer. Some background Hormone therapy is a prostate cancer treatment that targets the male sex hormones, such as testosterone, active in cancer. In some patients hormone therapy can cause side effects such as bone damage,...
Read MoreIntraductal carcinoma as an independent predictive factor in prostate biopsy
In a nutshell This study evaluated whether the presence of intraductal carcinoma of the prostate (IDC-P) in prostate biopsies predicts a poorer prognosis. Some background Prostate cancer is often a slow growing cancer with good prognosis (the predicted outcome of the disease is good). Unfortunately, in some cases relapse...
Read MoreIs early adjuvant radiotherapy associated with different outcomes compared to delayed therapy?
In a nutshell The authors evaluated the optimal timing of early versus delayed adjuvant radiotherapy following radical prostatectomy for locally advanced prostate cancer. Some background Radical prostatectomy (surgery to remove the prostate) remains the most common treatment for localized prostate cancer (has not spread beyond the prostate)...
Read MoreIGF-R; a new target for prostate cancer treatment?
In a nutshell This review explored the use of insulin-like growth factor receptor blockers as treatment for castration-resistant prostate cancer. Some background Prostate cancer is dependent on androgens, male hormones such as testosterone, for growth. Therefore androgen deprivation therapy, which blocks the production or action of testosterone...
Read MoreReducing the risk of bone fractures
In a nutshell This review examined the safety and efficacy of zoledronic acid (Zometa) and denosumab (Xgeva), two treatments for bone loss related to advanced prostate cancer. Some background Advanced prostate cancer (PC) can be associated with bone damage caused by bone metastases (cancer that has spread to the bones) or by androgen deprivation...
Read MoreSurgery or targeted radiotherapy?
In a nutshell This examined survival rates of radical prostatectomy compared with intensity modulated radiotherapy (IMRT) among patients with localized (confined) prostate cancer. Some background Radical prostatectomy or RP (surgical removal of the prostate gland and some healthy tissue around it) and radiotherapy are the most common...
Read MoreComparing therapies in the treatment of high-risk prostate cancer patients
In a nutshell This study compared the effects of different therapies in the treatment of high-risk prostate cancer. Failure of treatment and mortality rates were compared between the use of external beam radiotherapy (EBRT) and combined modality radiotherapy (CMRT). The effect of adding androgen deprivation therapy (ADT) to the treatment plan...
Read MoreComparing three different methods of radiation therapy and their effects on quality of life in patients with prostate cancer
In a nutshell This article looked at the effects of radiation therapy on bowel and urinary function in patients with prostate cancer. Three different methods of radiation therapy were compared:intensity-modulated radiotherapy (IMRT), proton beam therapy (PBT) and 3-dimensional conformal radiation therapy (3DCRT). Some background Radiation therapy...
Read MoreComparing survival for surgery versus radiation therapy in patients with prostate cancer
In a nutshell This study compared survival rates for patients with prostate cancer who were treated with either surgery to remove the prostate (radical prostatectomy) or radiation therapy (external beam radiotherapy). Some background The prostate is a gland in the reproductive system of men, which is found under the urinary bladder. In a...
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