In a nutshell This phase 1/2 trial will investigate BMS-986253, an experimental drug, in combination with nivolumab (Opdivo) to treat advanced cancer. The main outcomes will be the occurrence of side effects and tumor response. The details Advanced cancers have limited treatment options. New drugs are in development to improve patient prognosis. These...
Read MoreCurrent stage -Stage III Posts on Medivizor
Looking for men with high-risk prostate cancer features after prostate surgery to trial a type of radiation therapy
In a nutshell This trial is examining the effectiveness of radiation therapy, in treating patients with high-risk prostate cancer features after radical prostatectomy (surgery to remove the prostate gland). The main outcome to be measured will be freedom from failure. Failure is evidence that the cancer has returned. Patients will be followed up for 5...
Read MoreSearching for patients with stage 3-4 prostate cancer to test a treatment combination.
In a nutshell This trial is examining the effectiveness of radiation therapy with or without apalutamide (Erleada) in the treatment of stage 3-4 prostate cancer. The main outcome to be measured will be survival without cancer worsening. This trial is recruiting in Canada and the United States. The details Radiation therapy uses high energy x-ray...
Read MoreLooking for patients with advanced prostate cancer to test a type of radiation therapy
In a nutshell This trial evaluates a specific type of radiation therapy for advanced prostate cancer. The main outcome to be measured is whether or not the therapy will damage the surrounding organs. This trial is taking place in Pennsylvania, USA. The details Prostate cancer is an uncontrolled growth of the cells which make up the...
Read MoreApalutamide does not affect health-related quality of life in patients with localized prostate cancer
In a nutshell This study investigated the effect of apalutamide (Erleada) on health-related quality of life (H-QoL) in patients with prostate cancer. This study found that apalutimide preserved H-QoL while prolonging time taken for cancer to spread. Some background One treatment option for patients with prostate cancer is androgen...
Read MoreIs conventional or hypofractionated radiation therapy better for the treatment of prostate cancer?
In a nutshell This study compared two different types of radiation therapy after prostate surgery for prostate cancer, hypofractionated postprostatectomy radiation therapy (hypoPORT) and conventional postprostatectomy radiation therapy (coPORT). Results showed that hypoPORT may be effective in prostate cancer control and with similar side effects as...
Read MoreGuidelines for hypofractionated radiation therapy for localized prostate cancer
In a nutshell This study reviewed the current recommendations for treatment doses of radiation therapy for different stages of prostate cancer. Some background Hypo-fractionated radiation therapy (HFRT) for early-stage prostate cancer is a safe and effective treatment option. It involves a shorter course of treatment with larger doses...
Read MoreBetter survival for patients with new metastatic prostate cancer with previous prostate surgery
In a nutshell This study aimed to investigate the effect previous treatment has on overall survival for patients with metastatic (spread) prostate cancer. This study found that patients who had previous prostate surgery and radiation had improved overall survival. Some background Localized prostate cancer can be treated using prostate-removing...
Read MoreCyroablation for the treatment of early stage prostate cancer
In a nutshell This study evaluated the long-term safety and effectiveness of cryoablation (a process that uses extreme cold to destroy tissue) for patients with early prostate cancer. This study found that cryoablation is safe and effective for early-stage prostate cancer. Some background Cryoablation is a treatment option for early-stage prostate...
Read More2018 recommendations for the treatment of localized prostate cancer: Part II
In a nutshell This article reviewed treatment guidelines that have been recommended for patients with early-stage prostate cancer. Some background This analysis of existing treatment guidelines was done by the leading experts in prostate cancer research. They have made recommendations on the treatment of early-stage prostate cancer. Methods...
Read MoreComparing daily versus weekly imaging checks in radiation therapy for prostate cancer
In a nutshell This study aimed to investigate the best timing of treatment verification imaging used in radiation therapy for patients with prostate cancer. This study found that patients undergoing daily imaging had less risk of their cancer returning and had reduced rectal side-effects. Some background One main treatment option for prostate cancer...
Read MoreThe use of ADT and docetaxel in metastatic hormone-sensitive prostate cancer
In a nutshell This study aimed to discover if docetaxel (Taxotere) added to androgen-deprivation therapy (ADT) increases overall survival for patients with metastatic hormone-sensitive prostate cancer. This study found that overall survival was higher for patients who received ADT and docetaxel compared to those who took ADT. Some...
Read More
