In a nutshell This study investigated if reducing therapy duration could reduce side effects in patients but still be effective in patients with stage II colorectal cancer (CRC). This study showed that in certain patients a 3-month treatment duration can be considered. Some background Patients with colorectal cancer (CRC) can be treated...
Read MoreCurrent stage?-Stage II Posts on Medivizor
Can intraoperative radiotherapy be used to treat early-stage breast cancer?
In a nutshell This article looked at 5-year outcomes of intraoperative radiation therapy (IORT) for breast cancer (BC). The authors found that IORT may have a higher rate of cancer return compared to whole-breast radiation therapy (WBRT). Some background BC is one of the most common forms of cancer found in women. Standard care for BC is usually a...
Read MoreAdding S-1 to hormonal therapy in patients with ER+ HER2- breast cancer
In a nutshell This study investigated whether adding oral S-1 (Teysuno) to hormonal therapy improved outcomes in patients with estrogen receptor (ER)-positive and HER2-negative primary breast cancer (BC). The data showed that the combination of S-1 with hormonal therapy could be a potential treatment option for these patients. Some background...
Read MoreEvaluating long-term outcomes after high-intensity focused ultrasound for prostate cancer
In a nutshell This study evaluated the long-term outcomes of patients who underwent whole-gland high-intensity focused ultrasound (HIFU) for non-metastatic prostate cancer. The data showed that HIFU has favorable outcomes in low- and intermediate-risk groups of patients. Some background HIFU is a treatment option for prostate...
Read MoreEvaluating the use of radiotherapy followed by chemotherapy before surgery for locally-advanced rectal cancer.
In a nutshell This trial looked at the use of short-course radiotherapy (RT) followed by chemotherapy (CT) and delayed surgery to reduce distant metastases (tumor spread) in patients with locally advanced rectal cancer (LARC). The trial found that this treatment was more effective in controlling distant metastases when compared to standard...
Read MoreLooking for patients with breast reconstructions following breast surgery to trial a short radiation therapy
In a nutshell This trial is looking to examine the use of radiation on a shorter schedule of 5 days in a row is a safe and effective way to prevent breast cancer (BC) from coming back in people who have had a mastectomy (surgical removal of the breast). The main outcomes that are to be measured are local and regional disease recurrence. This trial is to...
Read MoreEvaluating radiation therapy after breast removal surgery for node-positive triple-negative breast cancer.
In a nutshell This study was carried out to assess the use of radiotherapy (RT) after mastectomy (surgical removal of the breast) for triple-negative breast cancer (TNBC) that has spread to the lymph nodes. The authors found that RT after surgery was associated with improved survival in patients with larger tumors. Some background Triple-negative...
Read MoreEvaluating long-term active surveillance for early-stage prostate cancer.
In a nutshell This study was carried out to assess the long-term outcomes of men diagnosed with prostate cancer (PC) undergoing active surveillance (AS) and factors that predicted the risk of their cancer spreading (metastasizing). The authors found that AS is a safe and viable option for men with low-risk and carefully-selected intermediate-risk...
Read MoreShould patients with prostate cancer get androgen deprivation therapy before or after radiotherapy?
In a nutshell This study compared the effectiveness of giving androgen deprivation therapy (ADT) before or after radiotherapy (RT) for prostate cancer (PCa). The study found that treatment with RT followed by ADT increased patient survival without the spread of the disease. Some background PCa can often spread to other locations within the...
Read MoreComparing whole-pelvis vs prostate only radiotherapy in patients with high-risk prostate cancer
In a nutshell This study compared the use of radiotherapy for prostate cancer in two areas: the prostate only, or the whole pelvis. The results showed that, for high-risk patients, radiotherapy of the whole pelvis improved patient outcomes. Some background For patients with medium or high-risk prostate cancer, the standard treatment is...
Read MoreEvaluating high-intensity focused ultrasound for prostate cancer
In a nutshell This study investigated the effect of high-intensity focused ultrasound (HIFU) on the function and outcomes of patients with localized prostate cancer (PCa). The data showed that treatment with HIFU on half of the prostate gland leads to better functional outcomes than the standard treatment. Some background...
Read MoreAre radiotherapy and surgery equally good at treating localized prostate cancer?
In a nutshell This study compared surgery and radiotherapy for treating localized prostate cancer. They found no significant difference in survival between the two treatments. Some background Localized prostate cancer (cancer which has not spread beyond the prostate gland) can be treated with either surgery, radiotherapy, or monitoring without...
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