In a nutshell This study examined the effect of combined radiation and hormone therapy on long-term fatigue. Researchers reported severe fatigue during and up to 4 years after treatment. Men with increased cancer markers and symptoms were more likely to report higher fatigue levels. Some background Radiation therapy and hormone therapy are often...
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Lower PSA levels increase or decrease mortality risk depending on Gleason score
In a nutshell This study evaluated prostate-specific mortality risk based on PSA (prostate specific antigen) levels in men with high-grade disease. Authors reported increased mortality risk with lower PSA levels in men with high-grade disease. A decreased mortality risk was observed with lower PSA levels in men with low-grade disease. Some background...
Read MoreLow-risk prostate cancer: Predictors of disease progression during active surveillance
In a nutshell This review examined predictors of disease progression in low-risk prostate cancer during active surveillance. Researchers concluded that certain blood markers, biopsy results, and ethnicity could help predict which patients were more likely to experience disease progression. Some background Active surveillance of prostate...
Read MoreLDH as an early predictor of cancer survival
In a nutshell This study investigated the relationship between lactate dehydrogenase (LDH) levels and cancer-specific survival. Researchers concluded that LDH can be used as an early indicator of cancer outcomes. Some background Early cancer detection methods have significantly improved cancer survival rates. There is increasing evidence to...
Read MoreTreating recurrent prostate cancer with lymph node surgery
In a nutshell The authors aimed to determine the long-term outcomes of lymph node surgery in patients who experienced prostate cancer recurrence after prostate surgery. Some background Prostate surgery involves surgically removing the prostate gland in patients with prostate cancer. In some cases, following surgery, some patients may experience...
Read MoreIdentifying prostate cancer progression
In a nutshell The authors aimed to identify the best options available to identify metastatic prostate cancer. Some background Metastatic prostate cancer is cancer that has spread from the prostate gland into tissues and organs around the body. In some cases patients with metastatic cancer can become resistant to certain treatments, such as...
Read MoreThe complications associated with hormone therapy in advanced prostate cancer
In a nutshell The authors aimed to determine the complications of hormone therapy in patients with advanced prostate cancer. Some background Hormone therapy is a prostate cancer treatment that targets the male sex hormones, such as testosterone, active in cancer. In some patients hormone therapy can cause side effects such as bone damage,...
Read MoreSurgery vs radiotherapy in prostate cancer; differences in complications
In a nutshell This article compares the risk of complications following different treatment for prostate cancer; namely surgery and radiotherapy. Some background Prostatectomy is surgery to remove all or part of the prostate gland, and is one of the main treatments for prostate cancer. Radiotherapy is also often used, and this uses radiation...
Read MoreThe effects and benefits of radiation treatment in prostate cancer
In a nutshell The authors aimed to review existing evidence on the safety and effectiveness of hypofractionation in prostate cancer. Some background Radiation involves directing a beam of radiation at the site of the tumor with the aim of killing cancer cells present. Hypofractionation is a type of radiation therapy that involves receiving large,...
Read MoreSurgery or watchful waiting – how are mortality risks affected?
In a nutshell The authors aimed to determine long-term outcomes in prostate cancer patients following treatment with watchful waiting or prostate surgery. Some background In early prostate cancer, watchful waiting is a form of treatment that involves closely monitoring a patient to determine any signs of cancer progression, but does not involve...
Read MoreLong-term effects of early prostate cancer treatment
In a nutshell The authors aimed to determine the long-term effects of early prostate cancer treatment. Some background Early prostate cancer is usually treated with active surveillance, radiation therapy, androgen deprivation therapy or surgery. Active surveillance involves the monitoring of cancer progression in a patient without administering...
Read MoreImaging technology can be used in active surveillance to monitor prostate cancer
In a nutshell The authors aimed to determine how effective magnetic resonance imaging is in monitoring patients with prostate cancer undergoing active surveillance. Some background Active surveillance is used in patients with favorable-risk prostate cancer (very low or low risk – cancer cannot be felt or seen by imaging or is localised to...
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