In a nutshell This study investigated the effectiveness and safety of atezolizumab (Tecentriq) as an addition to chemotherapy before surgery for patients with early-stage triple-negative breast cancer (TNBC). The data showed that the combination is effective in improving treatment response in these patients. Some background...Read More
Current stage-Stage II Posts on Medivizor
Comparing accelerated partial-breast irradiation and whole-breast irradiation in patients with early breast cancer.
In a nutshell This trial was carried out to assess the long-term results of external-beam accelerated partial-breast irradiation (APBI) intensity-modulated radiation therapy (IMRT) compared to whole-breast irradiation (WBI) in early-stage breast cancer (BC). The authors found that the 10-year recurrence of breast tumors was similar between the 2 methods,...Read More
Comparing hormone therapy and radiation after breast conserving surgery for older patients with early-stage breast cancer
In a nutshell This study compared the survival rates for older patients with early-stage breast cancer (BC) receiving hormone therapy (HT), radiation (RT), both or none after breast-conserving surgery (BCS). The data showed that RT and HT in combination and RT alone may lead to higher survival expectancy than HT alone. Some...Read More
In a nutshell This trial evaluated strategies to improve diarrhea as a side effect of neratinib (Nerlynx) treatment in patients with HER2-positive breast cancer (BC). The authors showed that slowly increasing the doses of neratinib or taking anti-diarrhea medication can improve this side effect. Some background Neratinib (Nerlynx) is a targeted...Read More
In a nutshell This study evaluated whether the safety and effectiveness of iodine (I)-seeded brachytherapy (IBT) for the treatment of NSCLC in older people. The study found that CT-guided IBT is an effective and safe therapy and can be considered as an alternative to surgery and radiotherapy for elderly patients with NSCLC. Some background...Read More
Long term effects of hypofractionated prone intensity-modulated radiation therapy after breast conservation surgery in patients with breast cancer
In a nutshell The study evaluated long-term outcomes of combining hypofractionated intensity-modulated radiation therapy (H-IMRT) with prone-positioning in patients after conservation surgery for breast cancer. The authors found that this combination safely controlled cancer locally without affecting regional lymph nodes. Some background Adjuvant...Read More
Is completion of irinotecan chemotherapy associated with better treatment response in locally advanced rectal cancer?
In a nutshell This study investigated the effectiveness of high completion of irinotecan (Camptosar) chemotherapy before locally advanced rectal cancer surgery. Researchers suggested that the completion of irinotecan chemotherapy was associated with better tumor response in these patients. Some background Colorectal cancer is the third most...Read More
In a nutshell The study evaluated the contribution of chemotherapy on cancer-related cognitive impairment (CRCI) reported by women with early breast cancer. The authors found that chemotherapy added to hormonal therapy caused early and short-term CRCI in such patients, compared to hormonal therapy alone. Some background CRCI refers to problems in...Read More
Does pembrolizumab added to chemotherapy before surgery improve the outcomes of patients with early triple negative breast cancer?
In a nutshell The study assessed whether pembrolizumab (Keytruda) could be used in addition to neoadjuvant chemotherapy (NAC; chemotherapy before surgery) to improve the outcomes of patients with early triple-negative breast cancer (TNBC). The study found that more patients treated with pembrolizumab had a complete response. Some...Read More
In a nutshell This study investigated the effect of atezolizumab (Tecentriq) with chemotherapy before surgery in non-small cell lung cancer (NSCLC). They found that this treatment before surgery was safe and effective. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung cancer (LC)....Read More
Cytokine-induced killer cell immunotherapy after surgery improves the outcomes of advanced colorectal cancer
In a nutshell This study investigated the effectiveness of the combined treatment with cytokine-induced killer cell (CIKC) immunotherapy and chemotherapy after surgery in colorectal cancer. Researchers suggested that this therapy improves treatment outcomes in patients with colorectal cancer. Some background Colorectal cancer is one of the most common...Read More
In a nutshell This study investigated the cardiovascular effects of chemotherapy after colorectal cancer (CRC) surgery. Researchers suggested that this treatment increases the stiffness of blood vessels in patients with CRC. Some background Colorectal cancer is a major cause of cancer mortality. However, the mortality rate has decreased in the...Read More