In a nutshell This study investigated the effectiveness of surgery followed by chemotherapy without chemoradiotherapy (CRT) before surgery to treat rectal cancer. Researchers suggested that this treatment improves the outcomes of these patients. Some background Colorectal cancer is the third most common cancer worldwide. The standard...
Read MoreCurrent stage-Stage II Posts on Medivizor
Comparing letrozole and taselisib against letrozole and placebo before surgery in early stage breast cancer
In a nutshell This study aimed to investigate the combination of letrozole and taselisib as a neoadjuvant treatment (before surgery) in patients with hormone receptor-positive, HER2-negative, early stage breast cancer. This study concluded that this treatment...
Read MoreTalazoparib before surgery for patients with BRCA mutated breast cancer
In a nutshell This study aimed to investigate the effectiveness and safety of talazoparib as a neoadjuvant agent (treatment before surgery) in patients with BRCA mutation and operable breast cancer. This study concluded that this treatment was a safe and effective in these patients. Some...
Read MoreIs there a best duration of post-surgery chemotherapy in patients with colon cancer?
In a nutshell This study compared a 3-month with a 6-month chemotherapy treatment after colon cancer surgery. Researchers suggested that the duration of the treatment should be chosen according to the patient condition. Some background Colorectal cancer is one of the most common cancers worldwide. Stage 2 and 3 colon cancer are common and curable...
Read MoreSearching for patients with breast cancer to test an anti-fatigue treatment.
In a nutshell This phase 3 trial will investigate the effect of bupropion (Wellbutrin) to treat fatigue in patients with breast cancer (BC). The main outcomes will be fatigue, quality of life and depression. This trial is recruiting across the United States. The details After treatment for breast cancer (BC), many women report feeling...
Read MoreTrastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer
In a nutshell This study wanted to find out which treatment was better before surgery for patients with HER2-positive breast cancer, trastuzumab emtansine (Kadcycla) plus pertuzumab (Perjeta), or a standard treatment. The study found that patients treated with trastuzumab emtansine plus pertuzumab (TEP) were more likely to have cancer...
Read MoreRadiation vs. thermal – a comparison of strategies for the treatment of early lung cancer
In a nutshell This study compared stereotactic body radiation therapy (SBRT) and thermal ablative procedures (TAP) in early-stage non-small cell lung cancer (NSCLC). They found that overall survival (OS) was greater in SBRT-treated patients. Some background Non-small cell lung cancer (NSCLC) is the most common form of lung...
Read MoreIs chemotherapy immediately after colon cancer surgery safe and feasible?
In a nutshell This study investigated the impact of starting chemotherapy treatment immediately after colon cancer surgery. Researchers suggested that this option is safe. Some background Colorectal cancer is the third most common cancer worldwide. The standard treatment is surgery and chemotherapy. However, colon cancer surgery is associated with a...
Read MoreSearching for patients with locally advanced non-small cell lung cancer to test a chemoradiotherapy regimen
In a nutshell This trial is examining the effectiveness and safety of standard chemoradiation vs a PET base chemoradiation combination in patients with non-small cell lung carcinoma (NSCLC). The main outcomes to be measured will be side effects and survival without cancer growing or spreading. The details A treatment option for...
Read MoreLooking for participants with stage 2 to 4 rectal cancer to try a new targeted therapy treatment
In a nutshell This phase 2 trial is examining the effectiveness and safety of durvalumab (Imfinzi) in the treatment of advanced rectal cancer that is not prone to genetic abnormalities. The main outcomes to be measured will be tumor response to the treatment and side effects. This trial is being conducted in the US. The details The standard treatment...
Read MoreChemotherapy before breast conserving surgery in breast cancer – is there an increased risk of complications?
In a nutshell This study investigated the effect of neoadjuvant chemotherapy (NAC; chemotherapy before surgery) in patients undergoing oncoplastic breast-conserving surgery (OBCS). They found that NAC did not affect the rate of complications in OBCS. Some background Breast cancer (BC) can be treated using a number of strategies....
Read MoreLong-short radiation therapy before surgery is associated with better outcomes in stage 2 and 3 rectal cancer
In a nutshell This study compared the survival outcomes of patients with rectal cancer who underwent short- or long-course radiation therapy (RT). Researchers suggested that long-course RT was associated with greater tumor response and survival. Some background Colorectal cancer is the third most common cancer diagnosed in the United States. The...
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