In a nutshell This trial is examining the effectiveness and safety of standard chemoradiation vs a PET base chemoradiation combination in patients with non-small cell lung carcinoma (NSCLC). The main outcomes to be measured will be side effects and survival without cancer growing or spreading. The details A treatment option for...
Read MoreCurrent stage-Stage II Posts on Medivizor
Looking for participants with stage 2 to 4 rectal cancer to try a new targeted therapy treatment
In a nutshell This phase 2 trial is examining the effectiveness and safety of durvalumab (Imfinzi) in the treatment of advanced rectal cancer that is not prone to genetic abnormalities. The main outcomes to be measured will be tumor response to the treatment and side effects. This trial is being conducted in the US. The details The standard treatment...
Read MoreChemotherapy before breast conserving surgery in breast cancer – is there an increased risk of complications?
In a nutshell This study investigated the effect of neoadjuvant chemotherapy (NAC; chemotherapy before surgery) in patients undergoing oncoplastic breast-conserving surgery (OBCS). They found that NAC did not affect the rate of complications in OBCS. Some background Breast cancer (BC) can be treated using a number of strategies....
Read MoreLong-short radiation therapy before surgery is associated with better outcomes in stage 2 and 3 rectal cancer
In a nutshell This study compared the survival outcomes of patients with rectal cancer who underwent short- or long-course radiation therapy (RT). Researchers suggested that long-course RT was associated with greater tumor response and survival. Some background Colorectal cancer is the third most common cancer diagnosed in the United States. The...
Read MoreConsolidation chemotherapy before surgery improves the outcomes in advanced rectal cancer.
In a nutshell This study investigated the effectiveness and safety of consolidation chemotherapy after initial treatment in locally advanced rectal cancer. Researchers suggested that this treatment is safe and is associated with improved cancer outcomes. Some background Colorectal cancer is the fifth most common cancer. From all the colorectal...
Read MoreLooking for patients with early rectal cancer to test less invasive surgery with chemotherapy
In a nutshell This trial is examining the effectiveness of chemotherapy followed by a less invasive surgery for early rectal cancer. The main outcome will be the number of patients keeping their rectum. This trial is being conducted in Canada and the United States. The details Rectal cancer is one of the most common cancers in the US. The standard...
Read MoreTransanal endoscopic microsurgery after chemoradiotherapy improves rectal cancer outcomes
In a nutshell This study investigated long term rectal cancer outcomes in patients who received chemotherapy, radiation therapy, and transanal microsurgery. Researchers suggested that this treatment improves treatment outcomes and quality of life of patients. Some background The standard treatment for rectal cancer is surgery. However,...
Read MoreComparing two types of surgery for low rectal cancers
In a nutshell This study aimed to investigate two techniques used to treat low rectal cancer, abdominoperineal resection (APR) and intersphincteric resection (ISR). This study found there was no significant difference in long-term outcomes for APR and ISR. Some background APR is a common surgery to remove low rectal cancers. A low rectal...
Read MoreStereotactic body radiation therapy in patients with inoperable lung cancer
In a nutshell This study wanted to find out how well a treatment for lung cancer called stereotactic body radiation therapy works in patients with lung cancer that cannot be surgically removed. The study found that this treatment is effective in patients with lung cancer, and a higher dose of radiation is not any better than a lower dose. Some...
Read MoreJoint pain and falls among women with breast cancer on aromatase inhibitors.
In a nutshell This study wanted to find out if joint pain is associated with falling down in patients with breast cancer who were treated with aromatase inhibitors. The study found that the patients who reported having joint pain were more likely to have a fall than those who had no joint pain. Some background Aromatase inhibitors are medications...
Read MoreLymphocyte count reduction is associated with better rectal cancer outcomes
In a nutshell This study investigated the relationship between lymphocyte (a type of white blood cells) counts and treatment outcomes for patients with rectal cancer. Researchers suggested that lymphocyte count reduction may be caused by rectal cancer treatment and is associated with better tumor response. Some background Colorectal cancer is the...
Read MoreLength of treatment with trastuzumab in HER2+ early stage breast cancer
In a nutshell This study wanted to find out what the best length of treatment with trastuzumab (Herceptin) is for HER2+ early stage breast cancer. The study found that at least one year of treatment had the best results in terms of how well it worked, and the cost-effectiveness. Some background HER-2 positive breast cancer is a type of cancer where...
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