In a nutshell This study investigated the outcomes of radical prostatectomy (RP) without pelvic lymph node dissection (PLND) in patients with prostate cancer. The main finding was that 5 years after treatment, 100% of patients at low risk for cancer recurrence had survived. Some background PLND is surgery to remove the lymph nodes from the pelvis....
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In a nutshell This study aimed to evaluate the use of irreversible electroporation (IRE) in the treatment of prostate cancer. This study found that IRE had low side-effect rates and promising outcomes. Some background Irreversible electroporation (IRE) uses high-energy pulses of electricity to destroy cancer cells. The brand name for...
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In a nutshell This study investigated the effectiveness of local vs radical surgery in patients with rectal cancer. Researchers suggested that local surgery is associated with better outcomes in certain patients with early cancers. Some background Colorectal cancer is the third most common cancer in the US. The standard treatment options for these...
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In a nutshell This study investigated the effect of neoadjuvant chemotherapy (NAC; chemotherapy before surgery) in patients undergoing oncoplastic breast-conserving surgery (OBCS). They found that NAC did not affect the rate of complications in OBCS. Some background Breast cancer (BC) can be treated using a number of strategies....
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In a nutshell This study examined if vascular-targeted photodynamic therapy (VTPT), or active surveillance is more effective in the treatment of low-risk prostate cancer. This study concluded that patients who received VTPT were less likely to require radical therapy compared to those who underwent active surveillance. Some background...
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In a nutshell This study wanted to find out if adding the medication denosumab (Prolia, Xgeva) to cancer treatment for women with breast cancer reduces the risk of bone fractures. The study found that the patients treated with denosumab survived better, but there was no significant difference in the number of bone fractures. Some background Breast...
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In a nutshell This study investigated the outcomes of patients with rectal cancer who received enhanced recovery pathway (ERP) in combination with surgery. Researchers suggested that ERP was associated with longer overall survival. Some background The standard treatment for rectal cancer is surgery, chemotherapy and radiation therapy. However, rectal...
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In a nutshell This trial is examining the effectiveness of chemotherapy followed by a less invasive surgery for early rectal cancer. The main outcome will be the number of patients keeping their rectum. This trial is being conducted in Canada and the United States. The details Rectal cancer is one of the most common cancers in the US. The standard...
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In a nutshell This phase 2 trial will investigate the safety and effectiveness of a prostate cancer vaccine. The main outcome will be the rate of prostate cancer progression. The details Prostate cancer (PC) is cancer the originates in the prostate gland (PG). PC is very common, however, most men will recover from it. The progression of PC is...
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In a nutshell This study determined whether stereotactic body radiation therapy (SBRT) was more effective than standard radiotherapy in patients with inoperable non-small cell lung cancer. The study found that SBRT led to better survival outcomes for these patients, with minimal side effects. Some background Tumor removal by surgery is the standard of...
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In a nutshell This trial evaluates a specific type of radiation therapy for advanced prostate cancer. The main outcome to be measured is whether or not the therapy will damage the surrounding organs. This trial is taking place in Pennsylvania, USA. The details Prostate cancer is an uncontrolled growth of the cells which make up the...
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In a nutshell This study wanted to find out how well a treatment for lung cancer called stereotactic body radiation therapy works in patients with lung cancer that cannot be surgically removed. The study found that this treatment is effective in patients with lung cancer, and a higher dose of radiation is not any better than a lower dose. Some...
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